Smoking, maternal age, and fetal growth. 1985

S Cnattingius, and O Axelsson, and G Eklund, and G Lindmark

In a prospective clinical study from an unselected area-based population, the influence on birth weight for gestational age (standardized birth weight) was studied with special respect to risk factors for intrauterine growth retardation. Smoking was the most important risk factor: 16% of the mothers smoked at least ten cigarettes per day, and the influence of smoking on standardized birth weight was highly significant (P less than .001). Maternal age in itself had no effect on standardized birth weight. However, among smokers the reduction in standardized birth weight became more pronounced with increasing maternal age (P less than .001). Longterm smoking has been reported to increase the risk of severe placental complications. This study emphasizes that elderly smokers also must be considered to be at a higher risk than younger smokers for developing fetal growth disturbances.

UI MeSH Term Description Entries
D008423 Maternal Age The age of the mother in PREGNANCY. Age, Maternal,Ages, Maternal,Maternal Ages
D011247 Pregnancy The status during which female mammals carry their developing young (EMBRYOS or FETUSES) in utero before birth, beginning from FERTILIZATION to BIRTH. Gestation,Pregnancies
D011446 Prospective Studies Observation of a population for a sufficient number of persons over a sufficient number of years to generate incidence or mortality rates subsequent to the selection of the study group. Prospective Study,Studies, Prospective,Study, Prospective
D001724 Birth Weight The mass or quantity of heaviness of an individual at BIRTH. It is expressed by units of pounds or kilograms. Birthweight,Birth Weights,Birthweights,Weight, Birth,Weights, Birth
D005260 Female Females
D005317 Fetal Growth Retardation Failure of a FETUS to attain expected GROWTH. Growth Retardation, Intrauterine,Intrauterine Growth Retardation,Fetal Growth Restriction,Intrauterine Growth Restriction
D006801 Humans Members of the species Homo sapiens. Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D000375 Aging The gradual irreversible changes in structure and function of an organism that occur as a result of the passage of time. Senescence,Aging, Biological,Biological Aging
D012306 Risk The probability that an event will occur. It encompasses a variety of measures of the probability of a generally unfavorable outcome. Relative Risk,Relative Risks,Risk, Relative,Risks,Risks, Relative
D012907 Smoking Willful or deliberate act of inhaling and exhaling SMOKE from burning substances or agents held by hand. Smoking Behaviors,Smoking Habit,Behavior, Smoking,Behaviors, Smoking,Habit, Smoking,Habits, Smoking,Smoking Behavior,Smoking Habits

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