Clinical Reasoning: A 69-Year-Old Woman With Ophthalmoplegia. 2025

Hongxuyang Yu, and Jessica Frey
From the Department of Neurology, West Virginia University, Morgantown.

We report a case of a 69-year-old woman who presented with acute-onset ophthalmoplegia. The patient continued to deteriorate over the next 10 days, developing upper and lower extremity weakness, dysphagia, and dyspnea, which eventually required intubation. This case report highlights the differential diagnosis associated with this constellation of symptoms and reviews current guidelines for treatment options related to the underlying diagnosis.

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