Biomaterial Database

Incidence of malignancy in peripheral lymph node biopsy. 1985

V Sriwatanawongsa, and R Cardoso, and P Chang

A review was made of 62 lymph node biopsy procedures during a 12-month period, from January 1, 1982, to December 31, 1982. The overall diagnostic yield was 56.5 per cent. Malignant lymph nodes were found in 53.2 per cent of cases. Seventy-two and two-tenths per cent (72.2%) of all malignant lymph nodes were metastatic carcinoma, including 6.1 per cent of metastatic lymph nodes with unknown primary. Twenty-seven and three-tenths per cent (27.3%) of all malignant lymph nodes belonged to the lymphoma-leukemia group. Among all the superficial lymph node regions, enlarged supraclavicular lymph nodes are associated with the highest incidence (75%) of malignancy. Clinical features associated with high incidence malignancy were: age greater than 55 years (75.8%), duration of less than 1 month (66.6%)--particularly, with a history of previous malignancy (91.7%). The anatomic knowledge of regional lymphatic drainage is essential in localizing the primary lesion of a metastatic lymph node.

UI	MeSH Term	Description	Entries
D007938	Leukemia	A progressive, malignant disease of the blood-forming organs, characterized by distorted proliferation and development of leukocytes and their precursors in the blood and bone marrow. Leukemias were originally termed acute or chronic based on life expectancy but now are classified according to cellular maturity. Acute leukemias consist of predominately immature cells; chronic leukemias are composed of more mature cells. (From The Merck Manual, 2006)	Leucocythaemia,Leucocythemia,Leucocythaemias,Leucocythemias,Leukemias
D008198	Lymph Nodes	They are oval or bean shaped bodies (1 - 30 mm in diameter) located along the lymphatic system.	Lymph Node,Node, Lymph,Nodes, Lymph
D008207	Lymphatic Metastasis	Transfer of a neoplasm from its primary site to lymph nodes or to distant parts of the body by way of the lymphatic system.	Lymph Node Metastasis,Lymph Node Metastases,Lymphatic Metastases,Metastasis, Lymph Node
D008223	Lymphoma	A general term for various neoplastic diseases of the lymphoid tissue.	Germinoblastoma,Lymphoma, Malignant,Reticulolymphosarcoma,Sarcoma, Germinoblastic,Germinoblastic Sarcoma,Germinoblastic Sarcomas,Germinoblastomas,Lymphomas,Lymphomas, Malignant,Malignant Lymphoma,Malignant Lymphomas,Reticulolymphosarcomas,Sarcomas, Germinoblastic
D008297	Male		Males
D008875	Middle Aged	An adult aged 45 - 64 years.	Middle Age
D009333	Neck	The part of a human or animal body connecting the HEAD to the rest of the body.	Necks
D011336	Probability	The study of chance processes or the relative frequency characterizing a chance process.	Probabilities
D002648	Child	A person 6 to 12 years of age. An individual 2 to 5 years old is CHILD, PRESCHOOL.	Children
D002968	Clavicle	A bone on the ventral side of the shoulder girdle, which in humans is commonly called the collar bone.	Collar Bone,Bone, Collar,Bones, Collar,Clavicles,Collar Bones