[Localization of the primary action of amino acids leading to the stimulation of gastric secretion]. 1985

L S Vasilevskaia, and G K Shlygin

An attempt has been made to specify whether the stimulant action of amino acids on gastric secretion is related to their direct effect on the structures of the central nervous system or to the influence on certain peripheral receptor formations followed by information transmission to the nervous centres. Acute experiments on dogs were performed to compare the effect of amino acids injected to the carotid artery and to the peripheral vein. It was established that amino acids injected to the carotid artery produced a more rapidly developing and more pronounced secretory reaction of the gastric glands than amino acids injected to the peripheral vein. This fact may strongly indicate that the above effect of amino acids is linked with their direct action on brain structures.

UI MeSH Term Description Entries
D007269 Injections, Intra-Arterial Delivery of drugs into an artery. Injections, Intraarterial,Intra-Arterial Injections,Intraarterial Injections,Injection, Intra-Arterial,Injection, Intraarterial,Injections, Intra Arterial,Intra Arterial Injections,Intra-Arterial Injection,Intraarterial Injection
D007275 Injections, Intravenous Injections made into a vein for therapeutic or experimental purposes. Intravenous Injections,Injection, Intravenous,Intravenous Injection
D004285 Dogs The domestic dog, Canis familiaris, comprising about 400 breeds, of the carnivore family CANIDAE. They are worldwide in distribution and live in association with people. (Walker's Mammals of the World, 5th ed, p1065) Canis familiaris,Dog
D005745 Gastric Acidity Determination Gastric analysis for determination of free acid or total acid. Acidity Determination, Gastric,Acidity Determinations, Gastric,Determination, Gastric Acidity,Determinations, Gastric Acidity,Gastric Acidity Determinations
D005753 Gastric Mucosa Lining of the STOMACH, consisting of an inner EPITHELIUM, a middle LAMINA PROPRIA, and an outer MUSCULARIS MUCOSAE. The surface cells produce MUCUS that protects the stomach from attack by digestive acid and enzymes. When the epithelium invaginates into the LAMINA PROPRIA at various region of the stomach (CARDIA; GASTRIC FUNDUS; and PYLORUS), different tubular gastric glands are formed. These glands consist of cells that secrete mucus, enzymes, HYDROCHLORIC ACID, or hormones. Cardiac Glands,Gastric Glands,Pyloric Glands,Cardiac Gland,Gastric Gland,Gastric Mucosas,Gland, Cardiac,Gland, Gastric,Gland, Pyloric,Glands, Cardiac,Glands, Gastric,Glands, Pyloric,Mucosa, Gastric,Mucosas, Gastric,Pyloric Gland
D006863 Hydrogen-Ion Concentration The normality of a solution with respect to HYDROGEN ions; H+. It is related to acidity measurements in most cases by pH pH,Concentration, Hydrogen-Ion,Concentrations, Hydrogen-Ion,Hydrogen Ion Concentration,Hydrogen-Ion Concentrations
D000596 Amino Acids Organic compounds that generally contain an amino (-NH2) and a carboxyl (-COOH) group. Twenty alpha-amino acids are the subunits which are polymerized to form proteins. Amino Acid,Acid, Amino,Acids, Amino
D000818 Animals Unicellular or multicellular, heterotrophic organisms, that have sensation and the power of voluntary movement. Under the older five kingdom paradigm, Animalia was one of the kingdoms. Under the modern three domain model, Animalia represents one of the many groups in the domain EUKARYOTA. Animal,Metazoa,Animalia
D013268 Stimulation, Chemical The increase in a measurable parameter of a PHYSIOLOGICAL PROCESS, including cellular, microbial, and plant; immunological, cardiovascular, respiratory, reproductive, urinary, digestive, neural, musculoskeletal, ocular, and skin physiological processes; or METABOLIC PROCESS, including enzymatic and other pharmacological processes, by a drug or other chemical. Chemical Stimulation,Chemical Stimulations,Stimulations, Chemical
D013997 Time Factors Elements of limited time intervals, contributing to particular results or situations. Time Series,Factor, Time,Time Factor

Related Publications

L S Vasilevskaia, and G K Shlygin
January 1971, Arzneimittel-Forschung,
L S Vasilevskaia, and G K Shlygin
January 1987, Biulleten' eksperimental'noi biologii i meditsiny,
L S Vasilevskaia, and G K Shlygin
November 1978, Gastroenterology,
L S Vasilevskaia, and G K Shlygin
January 1986, Journal of pediatric gastroenterology and nutrition,
L S Vasilevskaia, and G K Shlygin
September 1966, The Journal of clinical investigation,
L S Vasilevskaia, and G K Shlygin
January 1976, Gastroenterology,
L S Vasilevskaia, and G K Shlygin
September 1977, The American journal of physiology,
L S Vasilevskaia, and G K Shlygin
October 1978, Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.),
L S Vasilevskaia, and G K Shlygin
September 1967, Praxis,
L S Vasilevskaia, and G K Shlygin
August 1963, Deutsche medizinische Wochenschrift (1946),
Copied contents to your clipboard!