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Weanling rats were fed a copper-deficient purified diet. The effects of varying the type of protein and supplements of copper and zinc on cardiovascular pathology and some biochemical parameters were investigated. It was found that cardiomyopathy developed in the copper-deficient groups. Milk powder caused significant exacerbation of this development relative to dietary casein or egg white. Angiopathy developed only when dietary zinc was 20 ppm. Dietary copper did not change this situation. Serum cholesterol was elevated when copper was low and casein or milk powder were the protein source. The data point to an interaction between type of protein and dietary copper or zinc in the pathogenesis of cardiovascular lesions.
K L Stemmer, and
H G Petering, and
L Murthy, and
V N Finelli, and
E E Menden
January 1977,
Journal of agricultural and food chemistry,
K L Stemmer, and
H G Petering, and
L Murthy, and
V N Finelli, and
E E Menden
October 1953,
Archives of biochemistry and biophysics,
K L Stemmer, and
H G Petering, and
L Murthy, and
V N Finelli, and
E E Menden
January 1999,
BioFactors (Oxford, England),
K L Stemmer, and
H G Petering, and
L Murthy, and
V N Finelli, and
E E Menden
January 2002,
Saudi medical journal,
K L Stemmer, and
H G Petering, and
L Murthy, and
V N Finelli, and
E E Menden
January 2023,
Journal of animal science,
K L Stemmer, and
H G Petering, and
L Murthy, and
V N Finelli, and
E E Menden
January 2010,
Wei sheng yan jiu = Journal of hygiene research,
K L Stemmer, and
H G Petering, and
L Murthy, and
V N Finelli, and
E E Menden
May 1984,
The Journal of nutrition,
K L Stemmer, and
H G Petering, and
L Murthy, and
V N Finelli, and
E E Menden
May 1991,
Pancreas,
K L Stemmer, and
H G Petering, and
L Murthy, and
V N Finelli, and
E E Menden
June 2015,
Comparative biochemistry and physiology. Part B, Biochemistry & molecular biology,
K L Stemmer, and
H G Petering, and
L Murthy, and
V N Finelli, and
E E Menden
February 2007,
The British journal of nutrition,
