Biomaterial Database

The effect of indigestible particles on digestive transit time and colonic motility in dogs and pigs. 1985

C Cherbut, and Y Ruckebusch

The myoelectric activity of the colon was examined in three dogs and three pigs when they were given a basal diet or a basal diet plus indigestible particles (IP), 2 mm in diameter, at 100 g/kg dry matter. The mean retention time was determined using coloured discs as a marker added to the daily meal. Colonic electromyograms of dogs and pigs given IP revealed a 30% reduction in the number of long spike bursts (LSB) when compared with controls. The other components, propulsive migrating spike bursts (MSB) or non-propulsive short spike bursts (SSB), were unchanged. Mean retention time was decreased from 28.6 h to 17.6 h in dogs and from 129 h to 94.2 h in pigs. These changes developed progressively during 3-4 d in both species, suggesting that the reduction in motor activity was an adaptation to the changes in bulk contents. From the decreased motility of the colon linked to the reduction of LSB and paralleled by an increased transit time, it was concluded that one of the functions of the LSB is to impede the passage of digesta.

UI	MeSH Term	Description	Entries
D003106	Colon	The segment of LARGE INTESTINE between the CECUM and the RECTUM. It includes the ASCENDING COLON; the TRANSVERSE COLON; the DESCENDING COLON; and the SIGMOID COLON.	Appendix Epiploica,Taenia Coli,Omental Appendices,Omental Appendix,Appendices, Omental,Appendix, Omental
D004063	Digestion	The process of breakdown of food for metabolism and use by the body.
D004285	Dogs	The domestic dog, Canis familiaris, comprising about 400 breeds, of the carnivore family CANIDAE. They are worldwide in distribution and live in association with people. (Walker's Mammals of the World, 5th ed, p1065)	Canis familiaris,Dog
D005243	Feces	Excrement from the INTESTINES, containing unabsorbed solids, waste products, secretions, and BACTERIA of the DIGESTIVE SYSTEM.
D005769	Gastrointestinal Motility	The motor activity of the GASTROINTESTINAL TRACT.	Intestinal Motility,Gastrointestinal Motilities,Intestinal Motilities,Motilities, Gastrointestinal,Motilities, Intestinal,Motility, Gastrointestinal,Motility, Intestinal
D000222	Adaptation, Physiological	The non-genetic biological changes of an organism in response to challenges in its ENVIRONMENT.	Adaptation, Physiologic,Adaptations, Physiologic,Adaptations, Physiological,Adaptive Plasticity,Phenotypic Plasticity,Physiological Adaptation,Physiologic Adaptation,Physiologic Adaptations,Physiological Adaptations,Plasticity, Adaptive,Plasticity, Phenotypic
D000818	Animals	Unicellular or multicellular, heterotrophic organisms, that have sensation and the power of voluntary movement. Under the older five kingdom paradigm, Animalia was one of the kingdoms. Under the modern three domain model, Animalia represents one of the many groups in the domain EUKARYOTA.	Animal,Metazoa,Animalia
D013552	Swine	Any of various animals that constitute the family Suidae and comprise stout-bodied, short-legged omnivorous mammals with thick skin, usually covered with coarse bristles, a rather long mobile snout, and small tail. Included are the genera Babyrousa, Phacochoerus (wart hogs), and Sus, the latter containing the domestic pig (see SUS SCROFA).	Phacochoerus,Pigs,Suidae,Warthogs,Wart Hogs,Hog, Wart,Hogs, Wart,Wart Hog
D013997	Time Factors	Elements of limited time intervals, contributing to particular results or situations.	Time Series,Factor, Time,Time Factor