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The results of treatment of 69 cases of advanced soft tissue sarcomas are presented. Patients were given various drug schemes including cisplatin. Overall response in the study group was 30%. Tumor appeared sensitive to the treatment in 49%. A combination of carminomycin, methotrexate, cyclophosphamide and cisplatin proved to be the most effective (39%). The scheme was effective in both untreated patients and those previously treated with adriamycin. Hematologic toxicity registered in 67% cases was the most severe complication involved in the treatment with the above drug regimen.
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