The nerve supply to 25 poles of muscle spindles in the monkey was reconstructed by light microscopy of serial 1-micron thick transverse sections of lumbrical muscles. Twenty of 60 motor axons that supplied the spindle poles were identified as skeletofusimotor (beta). Twenty-eight percent of the spindle poles were innervated by beta axons, in addition to gamma axons. Every beta-innervated spindle pole transected an endplate zone of extrafusal muscle. Most beta axons coinnervated extrafusal fibers rich in mitochondria and the nuclear bag1 or nuclear chain intrafusal fibers. All but two beta axons innervated one type of intrafusal fiber only. The intramuscular organization of beta motor system in lumbrical muscles of the monkey was similar to that of the cat tenuissimus muscle. The function of beta-innervated spindles may be preferentially to monitor mechanical disturbances arising from the activity of extrafusal muscle units with which they share motor innervation.