-transparent.png){kind=logo}
The role of modern techniques of 99mTc methylene diphosphonate bone imaging in the management of lymphoma patients was assessed by comparing results of 107 bone scans in 16 patients with Hodgkin's disease, and 45 patients with non-Hodgkin's lymphoma to simultaneous radiologic, clinical, and histopathologic features as well as to subsequent disease course. The sensitivity and specificity were both greater than or equal to 0.96 in both Hodgkin's disease and non-Hodgkin's lymphoma and the overall accuracy by site was 98%. The scan proved to be useful in the definition and follow-up of skeletal lymphomatous disease in both symptomatic and asymptomatic patients, and defined abnormalities which were not predicted by either serum alkaline phosphatase activity or the presence of bone marrow involvement. In no patient, however, did the bone scan result by itself alter either initial staging or estimates of extent of disease at the time of relapse. Bone scanning, therefore, cannot be recommended as a screening procedure in patients with lymphoma; rather, this test is best reserved for the definition and follow-up of skeletal metastases in patients with active, concomitant, extraosseous disease.
K C Anderson, and
W D Kaplan, and
R C Leonard, and
A T Skarin, and
G P Canellos
December 1979,
Radiology,
K C Anderson, and
W D Kaplan, and
R C Leonard, and
A T Skarin, and
G P Canellos
December 1984,
Urology,
K C Anderson, and
W D Kaplan, and
R C Leonard, and
A T Skarin, and
G P Canellos
May 1985,
Radioisotopes,
K C Anderson, and
W D Kaplan, and
R C Leonard, and
A T Skarin, and
G P Canellos
January 1979,
Clinical nuclear medicine,
K C Anderson, and
W D Kaplan, and
R C Leonard, and
A T Skarin, and
G P Canellos
March 2002,
Australasian radiology,
K C Anderson, and
W D Kaplan, and
R C Leonard, and
A T Skarin, and
G P Canellos
November 1977,
Radioisotopes,
K C Anderson, and
W D Kaplan, and
R C Leonard, and
A T Skarin, and
G P Canellos
August 1981,
Radioisotopes,
K C Anderson, and
W D Kaplan, and
R C Leonard, and
A T Skarin, and
G P Canellos
September 1978,
Rinsho hoshasen. Clinical radiography,
K C Anderson, and
W D Kaplan, and
R C Leonard, and
A T Skarin, and
G P Canellos
May 1986,
Kidney international,
K C Anderson, and
W D Kaplan, and
R C Leonard, and
A T Skarin, and
G P Canellos
January 1986,
International journal of radiation applications and instrumentation. Part A, Applied radiation and isotopes,
