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Glycogen synthetase and phosphorylase activity in slow and fast twitch skeletal muscle fibres in man. 1977

K Piehl, and J Karlsson

Glycogen synthetase (I + D) and phosphorylase (à + b) activity was determined in human skeletal muscle biopsies with different muscle fibre composition and in dissected an pooled batches of the two main muscle fibre types: slow twitch (ST) and fast twitch (FT), respectively. Glycogen synthetase (I + D) activity remained unchanged as the per cent of FT fibres increased, but phosphoyrlase (à + b) activity was found to increase. A similar activity pattern was found in dissected and FT fibres as compared to ST fibres, i.e. the same glycogen synthetase activity but heightened phosphoyrlase activity.

UI MeSH Term Description Entries
D009132 Muscles Contractile tissue that produces movement in animals. Muscle Tissue,Muscle,Muscle Tissues,Tissue, Muscle,Tissues, Muscle
D006005 Phosphorylases A class of glucosyltransferases that catalyzes the degradation of storage polysaccharides, such as glucose polymers, by phosphorolysis in animals (GLYCOGEN PHOSPHORYLASE) and in plants (STARCH PHOSPHORYLASE). Glucan Phosphorylase,Phosphorylase,alpha-Glucan Phosphorylases
D006006 Glycogen Synthase An enzyme that catalyzes the transfer of D-glucose from UDPglucose into 1,4-alpha-D-glucosyl chains. EC 2.4.1.11. Glycogen (Starch) Synthase,Glycogen Synthetase,Glycogen Synthase I,Synthase D,Synthase I,UDP-Glucose Glycogen Glucosyl Transferase,Synthase, Glycogen,Synthetase, Glycogen,UDP Glucose Glycogen Glucosyl Transferase
D006801 Humans Members of the species Homo sapiens. Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D000328 Adult A person having attained full growth or maturity. Adults are of 19 through 44 years of age. For a person between 19 and 24 years of age, YOUNG ADULT is available. Adults

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