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Probabilistic Mapping of Magnetic Resonance-Guided Focused Ultrasound (MRgFUS) Thalamotomy Targets in Essential Tremor and Tremor-Dominant Parkinson's Disease: Insights from a German Cohort. 2025
Jonas Krauss, and
Neeraj Upadhyay, and
Veronika Purrer, and
Valeri Borger, and
Marcel Daamen, and
Hannah Weiland, and
Angelika Maurer, and
Carsten Schmeel, and
Alexander Radbruch, and
Markus Essler, and
Ullrich Wüllner, and
Henning Boecker
Clinical Functional Imaging Group, Department of Nuclear Medicine, University Hospital Bonn, Bonn, Germany.
Precise targeting in magnetic resonance-guided focused ultrasound (MRgFUS) is critical for effective tremor control in essential tremor and tremor-dominant Parkinson's disease, as small deviations can reduce efficacy or cause side effects. In our cohort, sweetspots were identified at Montreal Neurological Institute (MNI) coordinates x = -12.4, y = -17.5, z = -1.7 (ET) and x = -13.4, y = -19.8, z = -3.0 (TDPD).
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