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This study measured missed bone diagnosis on CT performed for lymph nodes or visceral spread of cancers and lymphomas. A bone-expert reading was compared to that of visceral-cancer oriented observers. From 100 examinations, 65% of bone abnormalities were not described by current reporting of cancer cases. Changes in windowing and contrast of the image produced large variations in CT readings. A slow search with different windowing decreases the false-negative ratio. A fast reading with invariable viewing parameters increases false interpretations, even for experienced radiologists.
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