Biomaterial Database

[Evaluation of the dose in permanent implants of I-125]. 1985

A Piermattei, and G Arcovito, and F Andreasi Bassi, and G D'Abramo

The Anderson's nomograph is currently used in 125I implants planning. For a given treatment volume, this method provides the activity and the seeds number and spacing. In order to obtain indications of the dose delivered in that 125I volume implants, we computed the average peripheral dose (APD), the average tumor dose (ATD) and the "matched peripheral dose" (MPD), for spherical, ellypsoidal and cylindrical volumes. By using the 125I source dosimetric data, we found that both the APD and the ATD are independent of sources randomizing in both position and orientation. Therefore the 125I seeds can be considered as point sources, provided that the dose values are scaled down by a factor which accounts for the spatial distribution anisotrophy. Since the computed parameters are only dependent on the implanted activity, the L. L. Anderson method can be applied even if brachytherapy treatments are associated with external beam radiotherapy ("boost"-therapy).

UI	MeSH Term	Description	Entries
D007457	Iodine Radioisotopes	Unstable isotopes of iodine that decay or disintegrate emitting radiation. I atoms with atomic weights 117-139, except I 127, are radioactive iodine isotopes.	Radioisotopes, Iodine
D009369	Neoplasms	New abnormal growth of tissue. Malignant neoplasms show a greater degree of anaplasia and have the properties of invasion and metastasis, compared to benign neoplasms.	Benign Neoplasm,Cancer,Malignant Neoplasm,Tumor,Tumors,Benign Neoplasms,Malignancy,Malignant Neoplasms,Neoplasia,Neoplasm,Neoplasms, Benign,Cancers,Malignancies,Neoplasias,Neoplasm, Benign,Neoplasm, Malignant,Neoplasms, Malignant
D011879	Radiotherapy Dosage	The total amount of radiation absorbed by tissues as a result of radiotherapy.	Dosage, Radiotherapy,Dosages, Radiotherapy,Radiotherapy Dosages
D001918	Brachytherapy	A collective term for interstitial, intracavity, and surface radiotherapy. It uses small sealed or partly-sealed sources that may be placed on or near the body surface or within a natural body cavity or implanted directly into the tissues.	Curietherapy,Implant Radiotherapy,Plaque Therapy, Radioisotope,Radioisotope Brachytherapy,Radiotherapy, Interstitial,Radiotherapy, Intracavity,Radiotherapy, Surface,Brachytherapy, Radioisotope,Interstitial Radiotherapy,Intracavity Radiotherapy,Radioisotope Plaque Therapy,Radiotherapy, Implant,Surface Radiotherapy,Therapy, Radioisotope Plaque
D003201	Computers	Programmable electronic devices designed to accept data, perform prescribed mathematical and logical operations at high speed, and display the results of these operations.	Calculators, Programmable,Computer Hardware,Computers, Digital,Hardware, Computer,Calculator, Programmable,Computer,Computer, Digital,Digital Computer,Digital Computers,Programmable Calculator,Programmable Calculators
D006801	Humans	Members of the species Homo sapiens.	Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man