Biomaterial Database

Conservation of hearing in acoustic neurilemmoma excision. 1977

M F Smith, and T P Clancy, and J S Lang

Conservation of hearing in acoustic neurilemmoma surgery is possible by the suboccipital route. The hearing preservation prognosis decreases as the size of the cerebellopontine angle neoplasm increases. Von Recklinghausen disease spells a poor prognosis for hearing. Some hearing was retained in seven of ten patients with preoperative hearing. Three patients retained postoperative hearing levels and speech sound discrimination equal to preoperative levels. One patient had a progressive high-frequency sensorineural hearing loss in the nontumor ear and was fitted with a hearing aid for the postoperative ear; he now has successful binaural hearing function. Gentle technique, microhemostasis, special instrumentation, and well-developed surgical craft are essential for preserving the microstructures necessary for hearing. Furthermore, the suboccipital approach for neurilemmomas less than 2 cm gives good surgical exposure and a reasonable chance to save hearing.

UI	MeSH Term	Description	Entries
D008297	Male		Males
D008875	Middle Aged	An adult aged 45 - 64 years.	Middle Age
D009442	Neurilemmoma	A neoplasm that arises from SCHWANN CELLS of the cranial, peripheral, and autonomic nerves. Clinically, these tumors may present as a cranial neuropathy, abdominal or soft tissue mass, intracranial lesion, or with spinal cord compression. Histologically, these tumors are encapsulated, highly vascular, and composed of a homogenous pattern of biphasic fusiform-shaped cells that may have a palisaded appearance. (From DeVita Jr et al., Cancer: Principles and Practice of Oncology, 5th ed, pp964-5)	Neurinoma,Schwannoma,Schwannomatosis, Plexiform,Neurilemoma,Neurilemmomas,Neurilemomas,Neurinomas,Plexiform Schwannomatoses,Plexiform Schwannomatosis,Schwannomas
D009456	Neurofibromatosis 1	An autosomal dominant inherited disorder (with a high frequency of spontaneous mutations) that features developmental changes in the nervous system, muscles, bones, and skin, most notably in tissue derived from the embryonic NEURAL CREST. Multiple hyperpigmented skin lesions and subcutaneous tumors are the hallmark of this disease. Peripheral and central nervous system neoplasms occur frequently, especially OPTIC NERVE GLIOMA and NEUROFIBROSARCOMA. NF1 is caused by mutations which inactivate the NF1 gene (GENES, NEUROFIBROMATOSIS 1) on chromosome 17q. The incidence of learning disabilities is also elevated in this condition. (From Adams et al., Principles of Neurology, 6th ed, pp1014-18) There is overlap of clinical features with NOONAN SYNDROME in a syndrome called neurofibromatosis-Noonan syndrome. Both the PTPN11 and NF1 gene products are involved in the SIGNAL TRANSDUCTION pathway of Ras (RAS PROTEINS).	Peripheral Neurofibromatosis,Recklinghausen Disease of Nerve,von Recklinghausen Disease,Cafe-au-Lait Spots with Pulmonic Stenosis,Molluscum Fibrosum,NF1 (Neurofibromatosis 1),Neurofibromatosis I,Neurofibromatosis Type 1,Neurofibromatosis Type I,Neurofibromatosis, Peripheral Type,Neurofibromatosis, Peripheral, NF 1,Neurofibromatosis, Peripheral, NF1,Neurofibromatosis, Type 1,Neurofibromatosis, Type I,Pulmonic Stenosis with Cafe-au-Lait Spots,Recklinghausen Disease, Nerve,Recklinghausen's Disease of Nerve,Recklinghausens Disease of Nerve,Watson Syndrome,von Recklinghausen's Disease,Cafe au Lait Spots with Pulmonic Stenosis,Neurofibromatoses, Peripheral,Neurofibromatoses, Type I,Neurofibromatosis, Peripheral,Peripheral Neurofibromatoses,Pulmonic Stenosis with Cafe au Lait Spots,Syndrome, Watson,Type 1 Neurofibromatosis,Type 1, Neurofibromatosis,Type I Neurofibromatoses,Type I, Neurofibromatosis,von Recklinghausens Disease
D010524	Peripheral Nervous System Neoplasms	Neoplasms which arise from peripheral nerve tissue. This includes NEUROFIBROMAS; SCHWANNOMAS; GRANULAR CELL TUMORS; and malignant peripheral NERVE SHEATH NEOPLASMS. (From DeVita Jr et al., Cancer: Principles and Practice of Oncology, 5th ed, pp1750-1)	Peripheral Nerve Neoplasms,Peripheral Nerve Neoplasms, Benign,Peripheral Nerve Neoplasms, Malignant,Peripheral Nerve Neoplastic Infiltration,Peripheral Nerve Tumors,Peripheral Nervous System Benign Neoplasms,Peripheral Nervous System Malignant Neoplasms,Neoplasm, Peripheral Nerve,Neoplasms, Peripheral Nerve,Nerve Neoplasm, Peripheral,Nerve Neoplasms, Peripheral,Nerve Tumor, Peripheral,Nerve Tumors, Peripheral,Peripheral Nerve Neoplasm,Peripheral Nerve Tumor,Tumor, Peripheral Nerve,Tumors, Peripheral Nerve
D011183	Postoperative Complications	Pathologic processes that affect patients after a surgical procedure. They may or may not be related to the disease for which the surgery was done, and they may or may not be direct results of the surgery.	Complication, Postoperative,Complications, Postoperative,Postoperative Complication
D003391	Cranial Nerves	Twelve pairs of nerves that carry general afferent, visceral afferent, special afferent, somatic efferent, and autonomic efferent fibers.	Cranial Nerve,Nerve, Cranial,Nerves, Cranial
D003638	Deafness	A general term for the complete loss of the ability to hear from both ears.	Deafness Permanent,Hearing Loss Permanent,Prelingual Deafness,Deaf Mutism,Deaf-Mutism,Deafness, Acquired,Hearing Loss, Complete,Hearing Loss, Extreme,Acquired Deafness,Complete Hearing Loss,Deafness, Prelingual,Extreme Hearing Loss,Permanent, Deafness,Permanent, Hearing Loss,Permanents, Deafness
D004428	Ear Neoplasms	Tumors or cancer of any part of the hearing and equilibrium system of the body (the EXTERNAL EAR, the MIDDLE EAR, and the INNER EAR).	Auricular Cancer,Auricular Neoplasms,Cancer of Ear,Ear Cancer,Cancer of Ear Auricle,Cancer of the Ear,Neoplasms of Ear Auricle,Neoplasms, Auricular,Neoplasms, Ear,Auricular Cancers,Cancer, Auricular,Cancers, Auricular,Ear Auricle Cancer,Ear Auricle Cancers,Ear Auricle Neoplasm,Ear Auricle Neoplasms,Ear Neoplasm,Neoplasm, Ear
D005260	Female		Females

Related Publications

M F Smith, and T P Clancy, and J S Lang

Otolaryngology-epitomes of progress: conservation of hearing in acoustic neurilemmoma excision.

July 1977, The Western journal of medicine,

M F Smith, and T P Clancy, and J S Lang

Hearing conservation in acoustic neurilemmoma surgery via the retrosigmoid approach.

April 1984, Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery,

M F Smith, and T P Clancy, and J S Lang

[Excision of an acoustic neuroma with conservation of hearing (author's transl)].

January 1981, Revue d'oto-neuro-ophtalmologie,

M F Smith, and T P Clancy, and J S Lang

Conservation of hearing in acoustic schwannoma surgery.

November 1985, The American journal of otology,

M F Smith, and T P Clancy, and J S Lang

Preserved hearing following excision of acoustic tumours.

July 1987, Lancet (London, England),

M F Smith, and T P Clancy, and J S Lang

Conservation of residual acoustic hearing after cochlear implantation.

December 2006, Otology & neurotology : official publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology,

M F Smith, and T P Clancy, and J S Lang

Hearing recovery following suboccipital excision of acoustic neuroma.

January 1988, Archives of otolaryngology--head & neck surgery,

M F Smith, and T P Clancy, and J S Lang

Hearing conservation in acoustic tumor surgery: pro's and con's.

April 1984, Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery,

M F Smith, and T P Clancy, and J S Lang

The contralateral ear in acoustic tumors and hearing conservation.

November 1981, The Laryngoscope,

M F Smith, and T P Clancy, and J S Lang

Acoustic neuroma surgery: the results of hearing conservation surgery.

July 1987, The Laryngoscope,