Biomaterial Database

Physiologic significance of the residual stomach after proximal gastrectomy from the view-point of serum gastrin. 1985

S Koga, and K Mizumoto

The physiological significance of the residual distal stomach after proximal gastrectomy (PG) was evaluated in dogs from the view-point of serum gastrin. The fasting gastrin levels in both (1/2 and 2/3) PG groups were high, especially in the 1/2 PG group. The serum gastrin levels did not decrease with time after test meal stimulation in both PG groups. This points to a disturbance of the short loop feedback mechanism in gastric secretion due to a reduction in gastric acid secretion. The elevated gastrin secretion after PG may be beneficial for postoperative digestion and absorption of food. Therefore, it is important when possible, to preserve the distal stomach of operated gastric cancer patients, and to select a reconstructive procedure which permits passage of food through the preserved distal stomach.

UI	MeSH Term	Description	Entries
D011863	Radioimmunoassay	Classic quantitative assay for detection of antigen-antibody reactions using a radioactively labeled substance (radioligand) either directly or indirectly to measure the binding of the unlabeled substance to a specific antibody or other receptor system. Non-immunogenic substances (e.g., haptens) can be measured if coupled to larger carrier proteins (e.g., bovine gamma-globulin or human serum albumin) capable of inducing antibody formation.	Radioimmunoassays
D004285	Dogs	The domestic dog, Canis familiaris, comprising about 400 breeds, of the carnivore family CANIDAE. They are worldwide in distribution and live in association with people. (Walker's Mammals of the World, 5th ed, p1065)	Canis familiaris,Dog
D005246	Feedback	A mechanism of communication within a system in that the input signal generates an output response which returns to influence the continued activity or productivity of that system.	Feedbacks
D005743	Gastrectomy	Excision of the whole (total gastrectomy) or part (subtotal gastrectomy, partial gastrectomy, gastric resection) of the stomach. (Dorland, 28th ed)	Gastrectomies
D005745	Gastric Acidity Determination	Gastric analysis for determination of free acid or total acid.	Acidity Determination, Gastric,Acidity Determinations, Gastric,Determination, Gastric Acidity,Determinations, Gastric Acidity,Gastric Acidity Determinations
D005755	Gastrins	A family of gastrointestinal peptide hormones that excite the secretion of GASTRIC JUICE. They may also occur in the central nervous system where they are presumed to be neurotransmitters.	Gastrin
D000818	Animals	Unicellular or multicellular, heterotrophic organisms, that have sensation and the power of voluntary movement. Under the older five kingdom paradigm, Animalia was one of the kingdoms. Under the modern three domain model, Animalia represents one of the many groups in the domain EUKARYOTA.	Animal,Metazoa,Animalia
D014628	Vagotomy	The interruption or removal of any part of the vagus (10th cranial) nerve. Vagotomy may be performed for research or for therapeutic purposes.	Vagotomies