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To try to obviate the difficulties encountered in making the differential diagnosis of the hyperkinetic form of multiple sclerosis (MS) and hepatocerebral dystrophy (HCD), the authors performed a biochemical study characterizing liver function in 27 patients with MS attended by hyperkineses and in 14 patients with HCD. In addition to clinical symptoms, patients with the hyperkinetic form of MS, contrary to those with HCD, had biochemical parameters characterizing the differences of liver function in these diseases. These findings facilitate the differential diagnosis between the hyperkinetic form of MS and HCD.
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