Effects of 3-acetylpyridine (3-AP) intoxication on the nervous system of mammals and birds. 1985

G Palmieri, and R Panu, and A Asole, and P L De Riu, and V Farina, and L Sanna

The authors studied, for the first time, the effects of 3-acetylpyridine administration on the nervous system of birds. The results were compared with those obtained in a mammal not studied yet. The data achieved from the guinea-pig confirmed substantially those got from other mammals, particularly from the rat. They pointed out the constant toxic action caused by the above drug inoculation on the central nervous system. The effects on birds are quite different: 3-AP administration, even at different doses from those employed in mammals, seldom provokes lesions of the central nervous system and the appearance of alterations does not depend on the considered species.

UI MeSH Term Description Entries
D007274 Injections, Intraperitoneal Forceful administration into the peritoneal cavity of liquid medication, nutrient, or other fluid through a hollow needle piercing the abdominal wall. Intraperitoneal Injections,Injection, Intraperitoneal,Intraperitoneal Injection
D009420 Nervous System The entire nerve apparatus, composed of a central part, the brain and spinal cord, and a peripheral part, the cranial and spinal nerves, autonomic ganglia, and plexuses. (Stedman, 26th ed) Nervous Systems,System, Nervous,Systems, Nervous
D011725 Pyridines Compounds with a six membered aromatic ring containing NITROGEN. The saturated version is PIPERIDINES.
D011784 Quail Common name for two distinct groups of BIRDS in the order GALLIFORMES: the New World or American quails of the family Odontophoridae and the Old World quails in the genus COTURNIX, family Phasianidae. Quails
D001921 Brain The part of CENTRAL NERVOUS SYSTEM that is contained within the skull (CRANIUM). Arising from the NEURAL TUBE, the embryonic brain is comprised of three major parts including PROSENCEPHALON (the forebrain); MESENCEPHALON (the midbrain); and RHOMBENCEPHALON (the hindbrain). The developed brain consists of CEREBRUM; CEREBELLUM; and other structures in the BRAIN STEM. Encephalon
D002529 Cerebellar Nuclei Four clusters of neurons located deep within the WHITE MATTER of the CEREBELLUM, which are the nucleus dentatus, nucleus emboliformis, nucleus globosus, and nucleus fastigii. Dentate Nucleus,Nucleus Dentatus,Nucleus Emboliformis,Nucleus Fastigii,Nucleus Globosus,Amiculum of the Dentate Nucleus,Anterior Interposed Nucleus,Anterior Interpositus Nucleus,Central Nuclei,Deep Cerebellar Nuclei,Dentate Cerebellar Nucleus,Fastigial Cerebellar Nucleus,Fastigial Nucleus,Intracerebellar Nuclei,Lateral Cerebellar Nucleus,Medial Cerebellar Nucleus,Central Nucleus,Cerebellar Nuclei, Deep,Cerebellar Nucleus,Cerebellar Nucleus, Deep,Cerebellar Nucleus, Dentate,Cerebellar Nucleus, Fastigial,Cerebellar Nucleus, Lateral,Cerebellar Nucleus, Medial,Deep Cerebellar Nucleus,Emboliformis, Nucleus,Fastigii, Nucleus,Globosus, Nucleus,Interposed Nucleus, Anterior,Interpositus Nucleus, Anterior,Intracerebellar Nucleus,Nuclei, Central,Nuclei, Cerebellar,Nuclei, Deep Cerebellar,Nuclei, Intracerebellar,Nucleus Fastigius,Nucleus, Anterior Interposed,Nucleus, Anterior Interpositus,Nucleus, Central,Nucleus, Cerebellar,Nucleus, Deep Cerebellar,Nucleus, Dentate,Nucleus, Dentate Cerebellar,Nucleus, Fastigial,Nucleus, Fastigial Cerebellar,Nucleus, Intracerebellar,Nucleus, Lateral Cerebellar,Nucleus, Medial Cerebellar
D002645 Chickens Common name for the species Gallus gallus, the domestic fowl, in the family Phasianidae, order GALLIFORMES. It is descended from the red jungle fowl of SOUTHEAST ASIA. Gallus gallus,Gallus domesticus,Gallus gallus domesticus,Chicken
D003391 Cranial Nerves Twelve pairs of nerves that carry general afferent, visceral afferent, special afferent, somatic efferent, and autonomic efferent fibers. Cranial Nerve,Nerve, Cranial,Nerves, Cranial
D005727 Ganglia, Spinal Sensory ganglia located on the dorsal spinal roots within the vertebral column. The spinal ganglion cells are pseudounipolar. The single primary branch bifurcates sending a peripheral process to carry sensory information from the periphery and a central branch which relays that information to the spinal cord or brain. Dorsal Root Ganglia,Spinal Ganglia,Dorsal Root Ganglion,Ganglion, Spinal,Ganglia, Dorsal Root,Ganglion, Dorsal Root,Spinal Ganglion
D006168 Guinea Pigs A common name used for the genus Cavia. The most common species is Cavia porcellus which is the domesticated guinea pig used for pets and biomedical research. Cavia,Cavia porcellus,Guinea Pig,Pig, Guinea,Pigs, Guinea

Related Publications

G Palmieri, and R Panu, and A Asole, and P L De Riu, and V Farina, and L Sanna
October 1979, Gaceta medica de Mexico,
G Palmieri, and R Panu, and A Asole, and P L De Riu, and V Farina, and L Sanna
September 1974, Brain research,
G Palmieri, and R Panu, and A Asole, and P L De Riu, and V Farina, and L Sanna
January 1980, Archivos de investigacion medica,
G Palmieri, and R Panu, and A Asole, and P L De Riu, and V Farina, and L Sanna
March 1980, The Journal of comparative neurology,
G Palmieri, and R Panu, and A Asole, and P L De Riu, and V Farina, and L Sanna
August 1982, Minerva medica,
G Palmieri, and R Panu, and A Asole, and P L De Riu, and V Farina, and L Sanna
September 2023, Veterinary research communications,
G Palmieri, and R Panu, and A Asole, and P L De Riu, and V Farina, and L Sanna
January 1975, Pharmacology, biochemistry, and behavior,
G Palmieri, and R Panu, and A Asole, and P L De Riu, and V Farina, and L Sanna
May 1982, The Canadian journal of neurological sciences. Le journal canadien des sciences neurologiques,
G Palmieri, and R Panu, and A Asole, and P L De Riu, and V Farina, and L Sanna
October 1984, Neuroscience research,
G Palmieri, and R Panu, and A Asole, and P L De Riu, and V Farina, and L Sanna
January 1984, Journal of neural transmission,
Copied contents to your clipboard!