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Epileptogenic mirror focus was produced in the left parietal area of the rat brain by cobalt implantation into the contralateral hemisphere. On the 14th day after cobalt implantation [3H]proline was injected into both experimental and control rats (without cobalt). The incorporation of [3H]proline in neurons of layers III and V of the parietal brain cortex and neurons of the nucleus lateralis thalami was investigated by the autoradiography technique. A statistically reliable increase in [3H]proline uptake was observed in neurons of layer III (31%) and in neurons of layer V (41%) of the epileptogenic mirror focus. The other neuronal types revealed no reliable changes. The morphological and functional aspects of the altered protein metabolism during epileptogenesis are discussed.
R M Khudoerkov, and
W Pohle, and
H Rüthrich, and
T Ott
November 1973,
Brain research,
R M Khudoerkov, and
W Pohle, and
H Rüthrich, and
T Ott
January 1981,
Cell and tissue research,
R M Khudoerkov, and
W Pohle, and
H Rüthrich, and
T Ott
February 1970,
Archives of oral biology,
R M Khudoerkov, and
W Pohle, and
H Rüthrich, and
T Ott
January 1977,
Neuroscience and behavioral physiology,
R M Khudoerkov, and
W Pohle, and
H Rüthrich, and
T Ott
January 1976,
Zhurnal nevropatologii i psikhiatrii imeni S.S. Korsakova (Moscow, Russia : 1952),
R M Khudoerkov, and
W Pohle, and
H Rüthrich, and
T Ott
January 1969,
Journal of dental research,
R M Khudoerkov, and
W Pohle, and
H Rüthrich, and
T Ott
February 1976,
Cell and tissue research,
R M Khudoerkov, and
W Pohle, and
H Rüthrich, and
T Ott
October 2003,
Nature neuroscience,
R M Khudoerkov, and
W Pohle, and
H Rüthrich, and
T Ott
January 1983,
Acta anatomica,
R M Khudoerkov, and
W Pohle, and
H Rüthrich, and
T Ott
July 1992,
Hippocampus,
