Cytoarchitectural fields and retinal termination: an axonal transport study of laminar organization in the avian optic tectum. 1985

B P Hayes, and K E Webster

The cytoarchitecture in the retinoreceptive zone of the pigeon optic tectum has been studied in Nissl-stained sections taken in four planes. As suggested by a previous study, two cytoarchitectural fields are present. Reconstructed views of the tectum show that the fields are separated by a narrow transition zone approximating to the tectal representation of the retina's horizontal meridian. In field 1 (which is upper and rostral), sublayer IIb is wide, IIc wide and trilaminate, IId narrow and IIe continuous; in field 2, IIb and c are narrow, IId wide and IIe discontinuous. The distribution of retinal terminals was investigated by the anterograde axonal transport of [3H]proline or horseradish peroxidase from intravitreal injections. The depth distribution of grains or reaction product throughout the entire tectum was quantified by scanning with a microdensitometer. Both autoradiography and horseradish peroxidase transport show two patterns of lamination separated by a narrow transition zone and these two terminal fields correspond closely to the cytoarchitectural fields. In field 1 optic terminals are concentrated in sublayer IIb, superficial c, d, and to a lesser extent in f; in field 2 concentrations are present at the IIb/c boundary, across deep IIc and d, and a small concentration is found IIf. The patterns of retinal termination with depth in the tectum found by axonal transport are compatible with those found by electron microscopy, and are discussed in relation to the optic termination found by other techniques. Study of the time course of axonal transport shows that both radioactive material and horseradish peroxidase are fast transported to all the bands of optic terminals at about 150 mm/day. Horseradish peroxidase gradually accumulates in the retinoreceptive zone, filling clusters of terminals and horizontal processes. At 12 days, it has begun to disappear from the zone and a few diffusely filled profiles, that may be transcellularly labelled, are present. Electron microscope autoradiography of fast transported material shows clusters of grains over optic terminals and preterminals and a percentage density analysis confirms that these profiles are specifically labelled. The two tectal fields each contain the projection from specialized areas of the retina, suggesting functional specialization in the tectum for the processing of different kinds of visual information.

UI MeSH Term Description Entries
D010856 Columbidae Family in the order COLUMBIFORMES, comprised of pigeons or doves. They are BIRDS with short legs, stout bodies, small heads, and slender bills. Some sources call the smaller species doves and the larger pigeons, but the names are interchangeable. Columba livia,Doves,Pigeons,Domestic Pigeons,Feral Pigeons,Rock Doves,Rock Pigeons,Domestic Pigeon,Dove,Dove, Rock,Doves, Rock,Feral Pigeon,Pigeon,Pigeon, Domestic,Pigeon, Feral,Pigeon, Rock,Pigeons, Domestic,Pigeons, Feral,Pigeons, Rock,Rock Dove,Rock Pigeon
D012160 Retina The ten-layered nervous tissue membrane of the eye. It is continuous with the OPTIC NERVE and receives images of external objects and transmits visual impulses to the brain. Its outer surface is in contact with the CHOROID and the inner surface with the VITREOUS BODY. The outer-most layer is pigmented, whereas the inner nine layers are transparent. Ora Serrata
D000818 Animals Unicellular or multicellular, heterotrophic organisms, that have sensation and the power of voluntary movement. Under the older five kingdom paradigm, Animalia was one of the kingdoms. Under the modern three domain model, Animalia represents one of the many groups in the domain EUKARYOTA. Animal,Metazoa,Animalia
D001345 Autoradiography The making of a radiograph of an object or tissue by recording on a photographic plate the radiation emitted by radioactive material within the object. (Dorland, 27th ed) Radioautography
D013477 Superior Colliculi The anterior pair of the quadrigeminal bodies which coordinate the general behavioral orienting responses to visual stimuli, such as whole-body turning, and reaching. Colliculus, Superior,Optic Lobe, Human,Optic Lobe, Mammalian,Optic Tectum,Anterior Colliculus,Superior Colliculus,Tectum, Optic,Colliculi, Superior,Colliculus, Anterior,Human Optic Lobe,Human Optic Lobes,Mammalian Optic Lobe,Mammalian Optic Lobes,Optic Lobes, Human,Optic Lobes, Mammalian,Optic Tectums,Tectums, Optic
D014795 Visual Pathways Set of cell bodies and nerve fibers conducting impulses from the eyes to the cerebral cortex. It includes the RETINA; OPTIC NERVE; optic tract; and geniculocalcarine tract. Pathway, Visual,Pathways, Visual,Visual Pathway

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