In this paper we have presented a 13-year-old boy whose unicameral bone cyst of the proximal humerus was, after sustaining a pathological fracture, obliterated with conservative management of the fracture. The literature is uncertain as to how many similar cases will go on to refracture union and cyst resolution. Therefore, we feel that invasive procedures should be delayed until the fracture heals. If healing of the cyst is not evident at six to eight weeks and if the cyst is small and monoloculated or adjacent to the growth plate, methylprednisolone acetate would be a recommended procedure. In cases of larger and/or multiloculated cysts or cysts that resist steroidal treatment, curettage and bone grafting is warranted.