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The activity of glucose-6-phosphate dehydrogenase (G-6-PD) in leucocytes was studied for erythrocyte G-6-PD deficiency using 49 hemizygous males, 16 heterozygous females, and 19 normal controls. The mean G-6-PD activity in leucocytes of the affected neonates (9.2 +/- 5.4 units) and the children (11.2 +/- 5.3 units) were significantly lower than those of normal newborns (22.9 +/- 5.1 units, P less than 0.01). Seventy percent of the effected newborns and 58% of the children with G-6-PD deficiency had the leucocyte enzyme activity of less than 13 IU/10(9)WBC. The leucocyte enzyme activity (14.6 +/- 8.6 units) of 16 heterozygous G-6-PD deficient mothers was also lower than that of normal controls (23.1 +/- 7.0 units). The present study thus concludes that, in G-6-PD deficient Chinese, the enzyme defect is demonstrable not only in erythrocytes but also in leucocytes.
S H Chen, and
K S Lin, and
C L Chen
October 1980,
European journal of pediatrics,
S H Chen, and
K S Lin, and
C L Chen
August 1963,
Maryland state medical journal,
S H Chen, and
K S Lin, and
C L Chen
November 1967,
Metabolism: clinical and experimental,
S H Chen, and
K S Lin, and
C L Chen
January 1973,
Nihon Naibunpi Gakkai zasshi,
S H Chen, and
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January 2003,
Blood cells, molecules & diseases,
S H Chen, and
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December 1973,
La Nouvelle presse medicale,
S H Chen, and
K S Lin, and
C L Chen
December 1967,
Indian journal of medical sciences,
S H Chen, and
K S Lin, and
C L Chen
January 1964,
Bulletin of the World Health Organization,
S H Chen, and
K S Lin, and
C L Chen
May 1975,
Indian pediatrics,
S H Chen, and
K S Lin, and
C L Chen
October 1965,
Nihon Ketsueki Gakkai zasshi : journal of Japan Haematological Society,
