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Fifteen patients with ulcerative colitis and 11 patients with ulcerative proctitis have been observed and studied for periods ranging from one to 15 years. It is suggested that the clinical course of the two disorders is quite distinct. Further, while the serum immunoglobulins were within normal limits in ulcerative proctitis, significant increases in the serum alpha(2)-, beta-, and gamma-globulins and in the IgA and IgG concentrations were found in ulcerative colitis. Despite total colectomy for ulcerative colitis, the serum IgG and IgA concentration remained high and even after subsequent rectal resection the relative IgA concentration continued to increase. The significance of these findings is discussed.
A H Smith, and
I W Macphee
September 1966,
Medicine,
A H Smith, and
I W Macphee
August 2012,
Alimentary pharmacology & therapeutics,
A H Smith, and
I W Macphee
January 1993,
Journal of internal medicine,
A H Smith, and
I W Macphee
December 1987,
Scandinavian journal of gastroenterology,
A H Smith, and
I W Macphee
March 1970,
Nihon Daicho Komonbyo Gakkai zasshi,
A H Smith, and
I W Macphee
April 2022,
Gastroenterologia y hepatologia,
A H Smith, and
I W Macphee
May 1985,
Ugeskrift for laeger,
A H Smith, and
I W Macphee
January 1982,
British medical journal (Clinical research ed.),
A H Smith, and
I W Macphee
December 1991,
Gut,
A H Smith, and
I W Macphee
August 2013,
Nihon Shokakibyo Gakkai zasshi = The Japanese journal of gastro-enterology,
