[UV-mutagenesis in Bacillus subtilis. VII. Induction of auxotrophic mutants]. 1977

O V Lotareva, and V D Filippov, and L I Panina

An experimental testing of material from thin-layered, transparent in passing light, colonies which appear with some frequency after plating Bacillus subtilis cells on agar medium with limited enrichment, has shown that such colonies are formed by auxotrophic mutants. The growth requirements for many of them has been identified. The most of mutants can be reversed to original phenotype by UV-irradiation. The frequency of auxotrophs increases after UV-irradiation of suspension of original cells. The sensitivity of auxotrophic mutants to inactivating action of UV-light is near to that of original cells, hence the increase of the frequency of mutants with dose is a result of induction, but not of selection of preexisting spontaneous auxotrophic mutants. The frequency of induced auxotrophs, in contrast to that of suppressor revertants, badly give way to declining in the time of temporary inhibition of postradiation growth. In the case of Bac, subtilis, the system of induced auxotrophic mutants on the medium with limited enrichment is rather comfortable in use and can be recommended for studying UV-induced mutagenesis in structural genes as well as for testing mutagenic activities.

UI MeSH Term Description Entries
D008967 Molecular Biology A discipline concerned with studying biological phenomena in terms of the chemical and physical interactions of molecules. Biochemical Genetics,Biology, Molecular,Genetics, Biochemical,Genetics, Molecular,Molecular Genetics,Biochemical Genetic,Genetic, Biochemical,Genetic, Molecular,Molecular Genetic
D009154 Mutation Any detectable and heritable change in the genetic material that causes a change in the GENOTYPE and which is transmitted to daughter cells and to succeeding generations. Mutations
D005827 Genetics, Microbial A subdiscipline of genetics which deals with the genetic mechanisms and processes of microorganisms. Microbial Genetics,Genetic, Microbial,Microbial Genetic
D001412 Bacillus subtilis A species of gram-positive bacteria that is a common soil and water saprophyte. Natto Bacteria,Bacillus subtilis (natto),Bacillus subtilis subsp. natto,Bacillus subtilis var. natto
D014466 Ultraviolet Rays That portion of the electromagnetic spectrum immediately below the visible range and extending into the x-ray frequencies. The longer wavelengths (near-UV or biotic or vital rays) are necessary for the endogenous synthesis of vitamin D and are also called antirachitic rays; the shorter, ionizing wavelengths (far-UV or abiotic or extravital rays) are viricidal, bactericidal, mutagenic, and carcinogenic and are used as disinfectants. Actinic Rays,Black Light, Ultraviolet,UV Light,UV Radiation,Ultra-Violet Rays,Ultraviolet Light,Ultraviolet Radiation,Actinic Ray,Light, UV,Light, Ultraviolet,Radiation, UV,Radiation, Ultraviolet,Ray, Actinic,Ray, Ultra-Violet,Ray, Ultraviolet,Ultra Violet Rays,Ultra-Violet Ray,Ultraviolet Black Light,Ultraviolet Black Lights,Ultraviolet Radiations,Ultraviolet Ray

Related Publications

O V Lotareva, and V D Filippov, and L I Panina
June 1988, Molekuliarnaia genetika, mikrobiologiia i virusologiia,
O V Lotareva, and V D Filippov, and L I Panina
January 1968, Acta microbiologica Academiae Scientiarum Hungaricae,
O V Lotareva, and V D Filippov, and L I Panina
January 2005, Applied and environmental microbiology,
O V Lotareva, and V D Filippov, and L I Panina
February 1991, Genetika,
O V Lotareva, and V D Filippov, and L I Panina
March 1964, Folia microbiologica,
O V Lotareva, and V D Filippov, and L I Panina
February 1979, Molecular & general genetics : MGG,
O V Lotareva, and V D Filippov, and L I Panina
January 1984, Molecular & general genetics : MGG,
O V Lotareva, and V D Filippov, and L I Panina
February 1988, Applied and environmental microbiology,
O V Lotareva, and V D Filippov, and L I Panina
June 1960, Journal of bacteriology,
O V Lotareva, and V D Filippov, and L I Panina
January 1975, Genetika,
Copied contents to your clipboard!