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Twenty-two patients with essential hypertension were treated for 3 months with pindolol, and blood pressure and plasma renin activity were measured at rest and after stimulation (upright posture stimulation and insulin induced hypoglycaemia stimulation). Beta-receptor blockade produced a significant decrease in systolic and diastolic blood pressure. After treatment with pindolol the plasma renin activity was significantly lower. Under conditions of renin stimulation such as orthostasis and insulin produced hypoglycaemia, plasma renin activity was significantly lower in treated patients. There was no correlation between the fall of plasma renin activity and the decrease of blood pressure. Renin suppression is probably only one of the factors involved in the reduction in the blood pressure in these patients.
I Tényi, and
M Németh, and
T Jávor, and
J Nemes, and
J Czimer
January 1977,
Kardiologia polska,
I Tényi, and
M Németh, and
T Jávor, and
J Nemes, and
J Czimer
November 1975,
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I Tényi, and
M Németh, and
T Jávor, and
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J Czimer
January 1983,
Orvosi hetilap,
I Tényi, and
M Németh, and
T Jávor, and
J Nemes, and
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June 1976,
Schweizerische medizinische Wochenschrift,
I Tényi, and
M Németh, and
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August 1980,
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I Tényi, and
M Németh, and
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J Nemes, and
J Czimer
January 1977,
Bollettino della Societa italiana di cardiologia,
I Tényi, and
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September 1990,
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I Tényi, and
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I Tényi, and
M Németh, and
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J Nemes, and
J Czimer
June 1976,
British journal of clinical pharmacology,
I Tényi, and
M Németh, and
T Jávor, and
J Nemes, and
J Czimer
April 1977,
Polski tygodnik lekarski (Warsaw, Poland : 1960),
