Biomaterial Database

Vivalan, a new anti-depressant-report on an out-patient trial. 1977

K Z Hasan, and P Niaz

The study on 20 patients referred from the psychiatric out-patients of the Jinnah Postgraduate Medical Centre, who were given Vivalan showed marked improvement in 14 patients (70%). Three showed mild improvement while three did not respond. The drug appears to be an advance in the range of anti-depressants presently available. It is of interest to note that Vivalan is not tricyclic compound, nor does it inhibit monoamine oxidase in vitro.

UI	MeSH Term	Description	Entries
D008297	Male		Males
D008875	Middle Aged	An adult aged 45 - 64 years.	Middle Age
D009025	Morpholines		Tetrahydro-1,4-Oxazines,Tetrahydro 1,4 Oxazines
D003863	Depression	Depressive states usually of moderate intensity in contrast with MAJOR DEPRESSIVE DISORDER present in neurotic and psychotic disorders.	Depressive Symptoms,Emotional Depression,Depression, Emotional,Depressive Symptom,Symptom, Depressive
D004341	Drug Evaluation	Any process by which toxicity, metabolism, absorption, elimination, preferred route of administration, safe dosage range, etc., for a drug or group of drugs is determined through clinical assessment in humans or veterinary animals.	Evaluation Studies, Drug,Drug Evaluation Studies,Drug Evaluation Study,Drug Evaluations,Evaluation Study, Drug,Evaluation, Drug,Evaluations, Drug,Studies, Drug Evaluation,Study, Drug Evaluation
D005260	Female		Females
D006801	Humans	Members of the species Homo sapiens.	Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D000275	Adjustment Disorders	Maladaptive reactions to identifiable psychosocial stressors occurring within a short time after onset of the stressor. They are manifested by either impairment in social or occupational functioning or by symptoms (depression, anxiety, etc.) that are in excess of a normal and expected reaction to the stressor.	Anniversary Reaction,Depression, Reactive,Reactive Disorders,Transient Situational Disturbance,Adjustment Disorder,Anniversary Reactions,Depressions, Reactive,Disorder, Adjustment,Disorder, Reactive,Disorders, Adjustment,Disorders, Reactive,Disturbance, Transient Situational,Disturbances, Transient Situational,Reaction, Anniversary,Reactions, Anniversary,Reactive Depression,Reactive Depressions,Reactive Disorder,Situational Disturbance, Transient,Situational Disturbances, Transient,Transient Situational Disturbances
D000328	Adult	A person having attained full growth or maturity. Adults are of 19 through 44 years of age. For a person between 19 and 24 years of age, YOUNG ADULT is available.	Adults
D000368	Aged	A person 65 years of age or older. For a person older than 79 years, AGED, 80 AND OVER is available.	Elderly