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Nanobodies: a new paradigm for brain disorder therapies. 2025
Institut de Génomique Fonctionnelle (IGF), University of Montpellier, CNRS, INSERM, 34094 Montpellier Cedex 5, France. Electronic address: pierre-andre.lafon@igf.cnrs.fr.
Camelid-derived nanobodies offer a promising alternative to conventional antibodies for the treatment of brain disorders. Their current development in models of schizophrenia or Alzheimer's disease highlights their strong therapeutic potential. Optimizing their delivery and ensuring their safety are major challenges, but their modularity and low immunogenicity make them promising candidates for neurotherapy.
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