Biomaterial Database

[Comparison of orthodromic and antidromic sensory nerve conduction. 2. Patients with polyneuropathies and polyradiculitis (author's transl)]. 1977

H P Ludin, and J Lütschg, and F Valsangiacomo

The results of the orthodromically and the antidromically recorded nerve action potentials from a median nerve in 30 patients with clinically slight or beginning polyneuropathies have been compared. Antidromic conduction velocity was slowed in 8 cases, in 8 patients it was normal and in 14 patients no definite antidromic nerve action potential could be recorded. This last finding is not considered as being definitely abnormal. In all but one patient orthodromic nerve action potentials could be elicited. In 28 out of 30 patients the orthodromic method gave pathological findings. Duration of the nerve action potentials and the number of their potential component were the most sensitive single parameters, which were abnormal in more cases than conduction velocity of the fastest fibres. For the detection of slight or beginning polyneuropathies the diagnostic yield of the orthodromic method turned out to be much greater than the antidromic. In contrast, in a group of 19 young patients, which previously had suffered from a polyradiculitis, no significant difference between the two methods was found.

UI	MeSH Term	Description	Entries
D008297	Male		Males
D008475	Median Nerve	A major nerve of the upper extremity. In humans, the fibers of the median nerve originate in the lower cervical and upper thoracic spinal cord (usually C6 to T1), travel via the brachial plexus, and supply sensory and motor innervation to parts of the forearm and hand.	Median Nerves,Nerve, Median,Nerves, Median
D008875	Middle Aged	An adult aged 45 - 64 years.	Middle Age
D009431	Neural Conduction	The propagation of the NERVE IMPULSE along the nerve away from the site of an excitation stimulus.	Nerve Conduction,Conduction, Nerve,Conduction, Neural,Conductions, Nerve,Conductions, Neural,Nerve Conductions,Neural Conductions
D011115	Polyneuropathies	Diseases of multiple peripheral nerves simultaneously. Polyneuropathies usually are characterized by symmetrical, bilateral distal motor and sensory impairment with a graded increase in severity distally. The pathological processes affecting peripheral nerves include degeneration of the axon, myelin or both. The various forms of polyneuropathy are categorized by the type of nerve affected (e.g., sensory, motor, or autonomic), by the distribution of nerve injury (e.g., distal vs. proximal), by nerve component primarily affected (e.g., demyelinating vs. axonal), by etiology, or by pattern of inheritance.	Polyneuropathy, Acquired,Polyneuropathy, Critical Illness,Polyneuropathy, Familial,Polyneuropathy, Inherited,Polyneuropathy, Motor,Acquired Polyneuropathies,Acquired Polyneuropathy,Critical Illness Polyneuropathies,Critical Illness Polyneuropathy,Familial Polyneuropathies,Familial Polyneuropathy,Inherited Polyneuropathies,Inherited Polyneuropathy,Motor Polyneuropathies,Motor Polyneuropathy,Polyneuropathies, Acquired,Polyneuropathies, Critical Illness,Polyneuropathies, Familial,Polyneuropathies, Inherited,Polyneuropathies, Motor,Polyneuropathy
D011128	Polyradiculopathy	Disease or injury involving multiple SPINAL NERVE ROOTS. Polyradiculitis refers to inflammation of multiple spinal nerve roots.	Polyradiculitis,Polyradiculopathy, Abdominal,Abdominal Polyradiculopathies,Abdominal Polyradiculopathy,Polyradiculitides,Polyradiculopathies,Polyradiculopathies, Abdominal
D011199	Potentiometry	Solution titration in which the end point is read from the electrode-potential variations with the concentrations of potential determining ions. (From McGraw-Hill Dictionary of Scientific and Technical Terms, 4th ed)
D005260	Female		Females
D006801	Humans	Members of the species Homo sapiens.	Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D000200	Action Potentials	Abrupt changes in the membrane potential that sweep along the CELL MEMBRANE of excitable cells in response to excitation stimuli.	Spike Potentials,Nerve Impulses,Action Potential,Impulse, Nerve,Impulses, Nerve,Nerve Impulse,Potential, Action,Potential, Spike,Potentials, Action,Potentials, Spike,Spike Potential