-transparent.png){kind=logo}
A possible extrathyroidal effect of propylthiouracil (PTU) and carbimazole on serum levels of thyroxine (T4), triiodothyronine (T3), 3,3',5'-triiodothyronine (reverse T3) and on thyrotrophin-releasing hormone (TRH) induced thyrotrophin (TSH) release was estimated in 19 patients with severe hypothyroidism treated with T4. During PTU medication a significant decrease in serum T3 from 90 +/- 16 (SD) to 79 +/- 23 ng/100 ml (P less than 0.01) and a reciprocal increase in serum reverse T3 from 51 +/- 14 (SD) to 58 +/- 20 ng/100 ml (P less than 0.025) were found. No significant changes in serum T4, basal serum TSH or response to TRH could be demonstrated. Carbimazole did not change any of the parameters studied.
K Siersbaek-Nielsen, and
C Kirkegaard, and
P Rogowski, and
J Faber, and
B Lumholtz, and
T Friis
January 1980,
The Indian journal of medical research,
K Siersbaek-Nielsen, and
C Kirkegaard, and
P Rogowski, and
J Faber, and
B Lumholtz, and
T Friis
May 2014,
Nigerian medical journal : journal of the Nigeria Medical Association,
K Siersbaek-Nielsen, and
C Kirkegaard, and
P Rogowski, and
J Faber, and
B Lumholtz, and
T Friis
April 1985,
Experimental and clinical endocrinology,
K Siersbaek-Nielsen, and
C Kirkegaard, and
P Rogowski, and
J Faber, and
B Lumholtz, and
T Friis
January 1987,
Reproduction, nutrition, developpement,
K Siersbaek-Nielsen, and
C Kirkegaard, and
P Rogowski, and
J Faber, and
B Lumholtz, and
T Friis
January 1977,
Endocrinologia experimentalis,
K Siersbaek-Nielsen, and
C Kirkegaard, and
P Rogowski, and
J Faber, and
B Lumholtz, and
T Friis
October 1983,
Zhongguo yi xue ke xue yuan xue bao. Acta Academiae Medicinae Sinicae,
K Siersbaek-Nielsen, and
C Kirkegaard, and
P Rogowski, and
J Faber, and
B Lumholtz, and
T Friis
August 1977,
The Journal of clinical endocrinology and metabolism,
K Siersbaek-Nielsen, and
C Kirkegaard, and
P Rogowski, and
J Faber, and
B Lumholtz, and
T Friis
January 1980,
Minerva pediatrica,
K Siersbaek-Nielsen, and
C Kirkegaard, and
P Rogowski, and
J Faber, and
B Lumholtz, and
T Friis
March 1980,
Acta endocrinologica,
K Siersbaek-Nielsen, and
C Kirkegaard, and
P Rogowski, and
J Faber, and
B Lumholtz, and
T Friis
January 1991,
Thyroid : official journal of the American Thyroid Association,
