-transparent.png){kind=logo}
The patients studied were diagnosed as suffering from alpha-chain disease by their clinicopathological features, malabsorption findings, X-ray, and presence of abnormal alpha-chain protein in their serum. The objective of the study was to determine any possible defect of the immune system in such patients. The rosette technique and surface immunofluorescence were used to enumerate the circulating T and B lymphocytes in these patients. They were also skin-tested with tuberculin and given sensitizing doses of dinitrochlorobenzene. Their serum immunoglobulins were also quantitated. It was found that the proportion of circulating B lymphocytes was much higher than normal, whereas that of T lymphocytes was lower than normal. Furthermore, they could not be sensitized to DNCB and their skin test to tuberculin was negative. It was concluded that the disease was a B-cell disease of IgA type, associated with low level of cellular immunity.
A Kharazmi, and
M H Rezai, and
P Abadi, and
K Nasr, and
P Haghighi, and
M Haghshenas
July 1978,
Comprehensive therapy,
A Kharazmi, and
M H Rezai, and
P Abadi, and
K Nasr, and
P Haghighi, and
M Haghshenas
June 1984,
Ophthalmology,
A Kharazmi, and
M H Rezai, and
P Abadi, and
K Nasr, and
P Haghighi, and
M Haghshenas
December 1973,
Zeitschrift fur Krebsforschung und klinische Onkologie. Cancer research and clinical oncology,
A Kharazmi, and
M H Rezai, and
P Abadi, and
K Nasr, and
P Haghighi, and
M Haghshenas
February 1987,
Transplantation proceedings,
A Kharazmi, and
M H Rezai, and
P Abadi, and
K Nasr, and
P Haghighi, and
M Haghshenas
February 1977,
Haematologica,
A Kharazmi, and
M H Rezai, and
P Abadi, and
K Nasr, and
P Haghighi, and
M Haghshenas
November 2012,
Journal of neuroimmunology,
A Kharazmi, and
M H Rezai, and
P Abadi, and
K Nasr, and
P Haghighi, and
M Haghshenas
June 1979,
Clinics in haematology,
A Kharazmi, and
M H Rezai, and
P Abadi, and
K Nasr, and
P Haghighi, and
M Haghshenas
July 2007,
Molecular immunology,
A Kharazmi, and
M H Rezai, and
P Abadi, and
K Nasr, and
P Haghighi, and
M Haghshenas
March 1992,
Immunology letters,
A Kharazmi, and
M H Rezai, and
P Abadi, and
K Nasr, and
P Haghighi, and
M Haghshenas
April 1973,
The Journal of clinical investigation,
