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Percutaneous needle aspiration was performed in three cases of cystic lesions of the adrenal gland which had been evaluated with nephrotomography, ultrasound, and angiography. The characteristics of the fluid aspirate were used as a guideline to further management. Two lesions were clearly benign cysts and were treated conservatively. The third lesion had a bloody aspirate and was surgically removed. The diagnostic evaluation of adrenal masses should follow a directed approach currently advocated for renal mass lesions.
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