Proceedings: Cis-N-2-arylcyclohexylamines and their quaternary ammonium salts--two new series of cholinesterase inhibitors. 1973

J W Lewis, and M J Readhead, and G Metcalf, and M H Smith, and P H McNally

UI MeSH Term Description Entries
D011759 Pyrrolidines Compounds also known as tetrahydropyridines with general molecular formula (CH2)4NH. Tetrahydropyridine,Tetrahydropyridines
D002800 Cholinesterase Inhibitors Drugs that inhibit cholinesterases. The neurotransmitter ACETYLCHOLINE is rapidly hydrolyzed, and thereby inactivated, by cholinesterases. When cholinesterases are inhibited, the action of endogenously released acetylcholine at cholinergic synapses is potentiated. Cholinesterase inhibitors are widely used clinically for their potentiation of cholinergic inputs to the gastrointestinal tract and urinary bladder, the eye, and skeletal muscles; they are also used for their effects on the heart and the central nervous system. Acetylcholinesterase Inhibitor,Acetylcholinesterase Inhibitors,Anti-Cholinesterase,Anticholinesterase,Anticholinesterase Agent,Anticholinesterase Agents,Anticholinesterase Drug,Cholinesterase Inhibitor,Anti-Cholinesterases,Anticholinesterase Drugs,Anticholinesterases,Cholinesterase Inhibitors, Irreversible,Cholinesterase Inhibitors, Reversible,Agent, Anticholinesterase,Agents, Anticholinesterase,Anti Cholinesterase,Anti Cholinesterases,Drug, Anticholinesterase,Drugs, Anticholinesterase,Inhibitor, Acetylcholinesterase,Inhibitor, Cholinesterase,Inhibitors, Acetylcholinesterase,Inhibitors, Cholinesterase,Inhibitors, Irreversible Cholinesterase,Inhibitors, Reversible Cholinesterase,Irreversible Cholinesterase Inhibitors,Reversible Cholinesterase Inhibitors
D003514 Cyclohexylamines A family of alicyclic hydrocarbons containing an amine group with the general formula R-C6H10NH2. Cyclohexylamine
D006801 Humans Members of the species Homo sapiens. Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D000818 Animals Unicellular or multicellular, heterotrophic organisms, that have sensation and the power of voluntary movement. Under the older five kingdom paradigm, Animalia was one of the kingdoms. Under the modern three domain model, Animalia represents one of the many groups in the domain EUKARYOTA. Animal,Metazoa,Animalia
D013329 Structure-Activity Relationship The relationship between the chemical structure of a compound and its biological or pharmacological activity. Compounds are often classed together because they have structural characteristics in common including shape, size, stereochemical arrangement, and distribution of functional groups. Relationship, Structure-Activity,Relationships, Structure-Activity,Structure Activity Relationship,Structure-Activity Relationships
D051381 Rats The common name for the genus Rattus. Rattus,Rats, Laboratory,Rats, Norway,Rattus norvegicus,Laboratory Rat,Laboratory Rats,Norway Rat,Norway Rats,Rat,Rat, Laboratory,Rat, Norway,norvegicus, Rattus

Related Publications

J W Lewis, and M J Readhead, and G Metcalf, and M H Smith, and P H McNally
December 1963, Bollettino della Societa italiana di biologia sperimentale,
J W Lewis, and M J Readhead, and G Metcalf, and M H Smith, and P H McNally
December 1963, Il Farmaco; edizione scientifica,
J W Lewis, and M J Readhead, and G Metcalf, and M H Smith, and P H McNally
January 1961, Therapie,
J W Lewis, and M J Readhead, and G Metcalf, and M H Smith, and P H McNally
July 1958, Science (New York, N.Y.),
J W Lewis, and M J Readhead, and G Metcalf, and M H Smith, and P H McNally
January 1984, Doklady Akademii nauk SSSR,
J W Lewis, and M J Readhead, and G Metcalf, and M H Smith, and P H McNally
September 1951, Biochimica et biophysica acta,
J W Lewis, and M J Readhead, and G Metcalf, and M H Smith, and P H McNally
December 1961, Meditsinskaia promyshlennost' SSSR,
J W Lewis, and M J Readhead, and G Metcalf, and M H Smith, and P H McNally
January 1952, Biochimica et biophysica acta,
J W Lewis, and M J Readhead, and G Metcalf, and M H Smith, and P H McNally
January 2002, Cellular & molecular biology letters,
J W Lewis, and M J Readhead, and G Metcalf, and M H Smith, and P H McNally
September 1986, Journal of the American Chemical Society,
Copied contents to your clipboard!