BIOMAT Database Logo BIOMAT Database Logo

Dihydrodigoxin: a common metabolite of digoxin in man. 1974

D R Clark, and S M Kalman

UI MeSH Term Description Entries
D002849 Chromatography, Gas Fractionation of a vaporized sample as a consequence of partition between a mobile gaseous phase and a stationary phase held in a column. Two types are gas-solid chromatography, where the fixed phase is a solid, and gas-liquid, in which the stationary phase is a nonvolatile liquid supported on an inert solid matrix. Chromatography, Gas-Liquid,Gas Chromatography,Chromatographies, Gas,Chromatographies, Gas-Liquid,Chromatography, Gas Liquid,Gas Chromatographies,Gas-Liquid Chromatographies,Gas-Liquid Chromatography
D004077 Digoxin A cardiotonic glycoside obtained mainly from Digitalis lanata; it consists of three sugars and the aglycone DIGOXIGENIN. Digoxin has positive inotropic and negative chronotropic activity. It is used to control ventricular rate in ATRIAL FIBRILLATION and in the management of congestive heart failure with atrial fibrillation. Its use in congestive heart failure and sinus rhythm is less certain. The margin between toxic and therapeutic doses is small. (From Martindale, The Extra Pharmacopoeia, 30th ed, p666) Digacin,Digitek,Digoregen,Digoxina Boehringer,Digoxine Nativelle,Dilanacin,Hemigoxine Nativelle,Lanacordin,Lanicor,Lanoxicaps,Lanoxin,Lanoxin-PG,Lenoxin,Mapluxin,Boehringer, Digoxina,Lanoxin PG,Nativelle, Digoxine,Nativelle, Hemigoxine
D006801 Humans Members of the species Homo sapiens. Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D013058 Mass Spectrometry An analytical method used in determining the identity of a chemical based on its mass using mass analyzers/mass spectrometers. Mass Spectroscopy,Spectrometry, Mass,Spectroscopy, Mass,Spectrum Analysis, Mass,Analysis, Mass Spectrum,Mass Spectrum Analysis,Analyses, Mass Spectrum,Mass Spectrum Analyses,Spectrum Analyses, Mass
D014316 Tritium The radioactive isotope of hydrogen also known as hydrogen-3. It contains two NEUTRONS and one PROTON in its nucleus and decays to produce low energy BETA PARTICLES. Hydrogen-3,Hydrogen 3

Related Publications

D R Clark, and S M Kalman
The development and application of a radioimmunoassay for dihydrodigoxin, a digoxin metabolite.
April 1982, The Journal of pharmacology and experimental therapeutics,
D R Clark, and S M Kalman
Formation of [20R]-dihydrodigoxin from digoxin in humans.
January 1985, Drug metabolism and disposition: the biological fate of chemicals,
D R Clark, and S M Kalman
Cross reactivity of dihydrodigoxin with a commercial digoxin kit.
June 1978, Clinical chemistry,
D R Clark, and S M Kalman
Cross reactivity of digoxin radioimmunoassay kits to dihydrodigoxin.
December 1982, Clinical chemistry,
D R Clark, and S M Kalman
Specificity of the digoxin radioimmunoassay with respect to dihydrodigoxin.
May 1976, Research communications in chemical pathology and pharmacology,
D R Clark, and S M Kalman
Increased metabolism to dihydrodigoxin after intake of a microencapsulated formulation of digoxin.
January 1984, European journal of clinical pharmacology,
D R Clark, and S M Kalman
Reduction of digoxin to 20R-dihydrodigoxin by cultures of Eubacterium lentum.
June 1986, Applied and environmental microbiology,
D R Clark, and S M Kalman
Fractionation of tritiated digoxin and dihydrodigoxin with DEAE-sephadex LH-20.
June 1976, Journal of chromatography,
D R Clark, and S M Kalman
Separation of digoxin and dihydrodigoxin by thin-layer or paper chromatography.
October 1976, Journal of chromatography,
D R Clark, and S M Kalman
Variability among commercially available digoxin radioimmunoassay kits in cross reactivity to dihydrodigoxin.
January 1978, Clinical chemistry,
Copied contents to your clipboard!