-transparent.png){kind=logo}
Metiamide, an antagonist of histamine H(2) receptors, was administered intravenously to normal subjects and to patients with a peptic ulcer during vagal stimulation with a constant infusion of insulin. In normal and peptic-ulcer subjects there were reductions of 70% and 71% respectively in gastric-acid output compared with control tests on the same subjects. The decreased acid output resulted from a reduction in both volume of secretion and acid concentration. Metiamide is therefore a potent inhibitor of vagally-induced gastric acid secretion.
Related Publications
D C Carter, and
J A Forrest, and
M Werner, and
R C Heading, and
J Park, and
D J Shearman
January 1974,
Surgical forum,
D C Carter, and
J A Forrest, and
M Werner, and
R C Heading, and
J Park, and
D J Shearman
March 1978,
The American journal of digestive diseases,
D C Carter, and
J A Forrest, and
M Werner, and
R C Heading, and
J Park, and
D J Shearman
December 1973,
British journal of pharmacology,
D C Carter, and
J A Forrest, and
M Werner, and
R C Heading, and
J Park, and
D J Shearman
May 1976,
South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde,
D C Carter, and
J A Forrest, and
M Werner, and
R C Heading, and
J Park, and
D J Shearman
January 1984,
Nephron,
D C Carter, and
J A Forrest, and
M Werner, and
R C Heading, and
J Park, and
D J Shearman
June 1977,
The New England journal of medicine,
D C Carter, and
J A Forrest, and
M Werner, and
R C Heading, and
J Park, and
D J Shearman
October 1983,
Scandinavian journal of gastroenterology,
D C Carter, and
J A Forrest, and
M Werner, and
R C Heading, and
J Park, and
D J Shearman
January 1983,
Polish journal of pharmacology and pharmacy,
D C Carter, and
J A Forrest, and
M Werner, and
R C Heading, and
J Park, and
D J Shearman
March 1975,
Gut,
D C Carter, and
J A Forrest, and
M Werner, and
R C Heading, and
J Park, and
D J Shearman
January 1984,
European journal of clinical pharmacology,
