[Effect of single impulses on cochlear microphone potentials of the guinea-pig cochlea]. 1977

M Biedermann, and G Büttner, and H Kaschowitz, and I Pingel

The influence of highly intensive single impulses on the cochlea of guinea pig was studied in an acute experiment. Very short impulses of less than or equal to 0.1 ms duration were produced by a sparknoise generator. The cochlear microphonics (CM) to a test stimulus (sinus tone, 3150 Hz) were recorded from the round window and measured prior to, during, and following impulse treatment. During the impulse treatment, the greatest amplitude reduction of CM occurred after the first impulse, while the further impulses caused a decreasing reduction. At first the number of impulses was varied: 1, 3, and 5 impulses were applied at intervals of 15 s each, at an impulse sound level of 164 dB sound pressure level re. 0.002 mubar (SPL). After these impulse treatments, in all cases a continual decrease of CM amplitudes up to a constant end value without recovery was found within a 2-hrs period of observation. The height of the end value depends on the number of impulses applied. Subsequently, at an exposure to 5 impluses the impulse sound level was stepwise reduced (164, 153, 144, 139 and 133 dB SPL). Again, a characteristic decrease of CM amplitudes was observed during the 2-hrs period of observation. The height of the end value is now dependent on the impluse sound level. Impulses of 164, 153 and 144 dB SPL cause a strong decrease of CM while the effect of impulses of 139 and 133 dB SPL is distinctly lower.

UI MeSH Term Description Entries
D008253 Macaca mulatta A species of the genus MACACA inhabiting India, China, and other parts of Asia. The species is used extensively in biomedical research and adapts very well to living with humans. Chinese Rhesus Macaques,Macaca mulatta lasiota,Monkey, Rhesus,Rhesus Monkey,Rhesus Macaque,Chinese Rhesus Macaque,Macaca mulatta lasiotas,Macaque, Rhesus,Rhesus Macaque, Chinese,Rhesus Macaques,Rhesus Macaques, Chinese,Rhesus Monkeys
D009991 Oscillometry The measurement of frequency or oscillation changes. Oscillometries
D003051 Cochlea The part of the inner ear (LABYRINTH) that is concerned with hearing. It forms the anterior part of the labyrinth, as a snail-like structure that is situated almost horizontally anterior to the VESTIBULAR LABYRINTH. Cochleas
D006168 Guinea Pigs A common name used for the genus Cavia. The most common species is Cavia porcellus which is the domesticated guinea pig used for pets and biomedical research. Cavia,Cavia porcellus,Guinea Pig,Pig, Guinea,Pigs, Guinea
D000161 Acoustic Stimulation Use of sound to elicit a response in the nervous system. Auditory Stimulation,Stimulation, Acoustic,Stimulation, Auditory
D000200 Action Potentials Abrupt changes in the membrane potential that sweep along the CELL MEMBRANE of excitable cells in response to excitation stimuli. Spike Potentials,Nerve Impulses,Action Potential,Impulse, Nerve,Impulses, Nerve,Nerve Impulse,Potential, Action,Potential, Spike,Potentials, Action,Potentials, Spike,Spike Potential
D000818 Animals Unicellular or multicellular, heterotrophic organisms, that have sensation and the power of voluntary movement. Under the older five kingdom paradigm, Animalia was one of the kingdoms. Under the modern three domain model, Animalia represents one of the many groups in the domain EUKARYOTA. Animal,Metazoa,Animalia
D000882 Haplorhini A suborder of PRIMATES consisting of six families: CEBIDAE (some New World monkeys), ATELIDAE (some New World monkeys), CERCOPITHECIDAE (Old World monkeys), HYLOBATIDAE (gibbons and siamangs), CALLITRICHINAE (marmosets and tamarins), and HOMINIDAE (humans and great apes). Anthropoidea,Monkeys,Anthropoids,Monkey
D001309 Auditory Threshold The audibility limit of discriminating sound intensity and pitch. Auditory Thresholds,Threshold, Auditory,Thresholds, Auditory

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