Biomaterial Database

Central giant cell granuloma and periapical fibrous dysplasia occurring in the same jaw. 1978

J Lustmann, and W A Soskolne, and J Lewin-Epstein

A 19-year-old woman presented with two tumorlike conditions in the mandible. Seven vital mandibular teeth were associated with periapical lesions. One periapical lesion was enucleated and histopathologic examination confirmed the diagnosis of periapical fibrous dysplasia. The second lesion was a large multilocular radiolucency which extended from the mandibular left premolars to the ascending ramus. It was diagnosed as a central giant cell granuloma despite having many features in common with those of an ossifying fibroma. The lesion was removed and healing was uneventful.

UI	MeSH Term	Description	Entries
D008334	Mandible	The largest and strongest bone of the FACE constituting the lower jaw. It supports the lower teeth.	Mylohyoid Groove,Mylohyoid Ridge,Groove, Mylohyoid,Grooves, Mylohyoid,Mandibles,Mylohyoid Grooves,Mylohyoid Ridges,Ridge, Mylohyoid,Ridges, Mylohyoid
D008336	Mandibular Diseases	Diseases involving the MANDIBLE.	Disease, Mandibular,Diseases, Mandibular,Mandibular Disease
D005260	Female		Females
D005357	Fibrous Dysplasia of Bone	A disease of bone marked by thinning of the cortex by fibrous tissue containing bony spicules, producing pain, disability, and gradually increasing deformity. Only one bone may be involved (FIBROUS DYSPLASIA, MONOSTOTIC) or several (FIBROUS DYSPLASIA, POLYOSTOTIC).	Osteitis Fibrosa Disseminata,Fibrocartilaginous Dysplasia of Bone,Fibrocystic Dysplasia of Bone,Jaffe-Lichtenstein Disease,Bone Fibrocartilaginous Dysplasia,Bone Fibrocartilaginous Dysplasias,Bone Fibrocystic Dysplasia,Bone Fibrocystic Dysplasias,Bone Fibrous Dysplasia,Bone Fibrous Dysplasias,Jaffe Lichtenstein Disease
D006101	Granuloma, Giant Cell	A non-neoplastic inflammatory lesion, usually of the jaw or gingiva, containing large, multinucleated cells. It includes reparative giant cell granuloma. Peripheral giant cell granuloma refers to the gingiva (giant cell epulis); central refers to the jaw.	Epulis, Giant Cell,Giant Cell Granuloma,Granuloma, Giant Cell Reparative,Epulides, Giant Cell,Peripheral Giant Cell Granuloma,Giant Cell Epulides,Giant Cell Epulis,Giant Cell Granulomas,Granulomas, Giant Cell
D006801	Humans	Members of the species Homo sapiens.	Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D000328	Adult	A person having attained full growth or maturity. Adults are of 19 through 44 years of age. For a person between 19 and 24 years of age, YOUNG ADULT is available.	Adults