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147 samples of punctured middle ear effusion fluid from cases of otitis media with effusion and 150 samples from patients with acute purulent otitis media were tested for lysozyme activity. In otitis media with effusion the concentration was 182.0 U/ml, in acute otitis 433.8 U/ml. The lysozyme concentration in otitis media with effusion depended upon the nature of the effusion. Serous fluid showed an activity of 124.8 U/ml and mucoid 311.6 U/ml, respectively. In culture-positive cases of acute otitis media the lysozyme level was 423.4 U/ml. Culture-negative cases showed about the same concentration, 438.3 U/ml. The possible role of lysozyme in defence systems of the middle ear is discussed.
S Virtanen, and
E A Lahikainen
January 1985,
Auris, nasus, larynx,
S Virtanen, and
E A Lahikainen
January 1990,
Archives of otolaryngology--head & neck surgery,
S Virtanen, and
E A Lahikainen
December 2012,
International journal of pediatric otorhinolaryngology,
S Virtanen, and
E A Lahikainen
August 1997,
The Pediatric infectious disease journal,
S Virtanen, and
E A Lahikainen
July 1991,
The Annals of otology, rhinology, and laryngology,
S Virtanen, and
E A Lahikainen
July 1998,
The Pediatric infectious disease journal,
S Virtanen, and
E A Lahikainen
January 1984,
Pediatric infectious disease,
S Virtanen, and
E A Lahikainen
September 1992,
The Laryngoscope,
S Virtanen, and
E A Lahikainen
May 2004,
Otology & neurotology : official publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology,
S Virtanen, and
E A Lahikainen
January 2016,
Kulak burun bogaz ihtisas dergisi : KBB = Journal of ear, nose, and throat,
