-transparent.png){kind=logo}
The tissue localization of antihemophilic factor (AHF, Factor VIII) has been determined by immunofluorescent studies using monospecific rabbit antibody to human AHF. Specific staining demonstrating AHF antigens has been identified in endothelial cells of a wide range of human tissues. The staining pattern was observed in endothelial cells of arteries, capillaries, and veins as well as the cells lining hepatic and splenic sinusoids. Specific fluorescence was limited to these endothelial cells in sections of kidney, liver, spleen, lymph node, cardiac and smooth muscle, thyroid, umbilical cord, and skin. Absorption studies established that the staining was specific for cells in which there were proteins that had AHF antigens. The demonstration of fluorescence within the cytoplasm of endothelial cells suggests that these cells synthesize proteins that have AHF antigens.
L W Hoyer, and
R P De los Santos, and
J R Hoyer
May 1974,
The Journal of clinical investigation,
L W Hoyer, and
R P De los Santos, and
J R Hoyer
November 1973,
The Journal of clinical investigation,
L W Hoyer, and
R P De los Santos, and
J R Hoyer
November 1978,
Thrombosis research,
L W Hoyer, and
R P De los Santos, and
J R Hoyer
November 1982,
The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society,
L W Hoyer, and
R P De los Santos, and
J R Hoyer
January 1981,
Biology of the neonate,
L W Hoyer, and
R P De los Santos, and
J R Hoyer
June 2014,
Physical chemistry chemical physics : PCCP,
L W Hoyer, and
R P De los Santos, and
J R Hoyer
November 1977,
British journal of cancer,
L W Hoyer, and
R P De los Santos, and
J R Hoyer
May 1992,
The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society,
L W Hoyer, and
R P De los Santos, and
J R Hoyer
June 1980,
The American journal of surgical pathology,
L W Hoyer, and
R P De los Santos, and
J R Hoyer
February 1981,
Clinical nephrology,
