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We typed 45 schizophrenic patients for 35 HLA antigens and compared their frequencies with 1,263 population controls. No significant differences between schizophrenics and controls were found. When the schizophrenics were subtyped, a significant (P less than .05) excess of Aw26 was found among the hebephrenics, compared with the population controls. When the published literature on schizophrenia-HLA associations was surveyed, none of the reported associations were found to be consistent across studies. Some possible explanations for the heterogeneity among studies are discussed and it is concluded that an association between schizophrenia and any of the HLA antigens has not yet been demonstrated.
R R Crowe, and
J S Thompson, and
R Flink, and
B Weinberger
January 1980,
Lancet (London, England),
R R Crowe, and
J S Thompson, and
R Flink, and
B Weinberger
April 1980,
Lancet (London, England),
R R Crowe, and
J S Thompson, and
R Flink, and
B Weinberger
January 1981,
Schweizer Archiv fur Neurologie, Neurochirurgie und Psychiatrie = Archives suisses de neurologie, neurochirurgie et de psychiatrie,
R R Crowe, and
J S Thompson, and
R Flink, and
B Weinberger
January 1981,
Zhurnal nevropatologii i psikhiatrii imeni S.S. Korsakova (Moscow, Russia : 1952),
R R Crowe, and
J S Thompson, and
R Flink, and
B Weinberger
March 1990,
Psychiatry research,
R R Crowe, and
J S Thompson, and
R Flink, and
B Weinberger
September 1976,
Tissue antigens,
R R Crowe, and
J S Thompson, and
R Flink, and
B Weinberger
October 1981,
Psychiatry research,
R R Crowe, and
J S Thompson, and
R Flink, and
B Weinberger
March 1991,
Biological psychiatry,
R R Crowe, and
J S Thompson, and
R Flink, and
B Weinberger
January 1984,
Human heredity,
R R Crowe, and
J S Thompson, and
R Flink, and
B Weinberger
March 1981,
Journal of affective disorders,
