Biomaterial Database

The C3 nephritic factor (C3NeF) and the heat labile complement inactivator (HLCI) in chronic hypocomplementemic mesangioproliferative glomerulonephritis. 1974

F C Berthoux, and C B Carpenter, and J Traeger, and J P Merrill

UI	MeSH Term	Description	Entries
D007668	Kidney	Body organ that filters blood for the secretion of URINE and that regulates ion concentrations.	Kidneys
D003165	Complement System Proteins	Serum glycoproteins participating in the host defense mechanism of COMPLEMENT ACTIVATION that creates the COMPLEMENT MEMBRANE ATTACK COMPLEX. Included are glycoproteins in the various pathways of complement activation (CLASSICAL COMPLEMENT PATHWAY; ALTERNATIVE COMPLEMENT PATHWAY; and LECTIN COMPLEMENT PATHWAY).	Complement Proteins,Complement,Complement Protein,Hemolytic Complement,Complement, Hemolytic,Protein, Complement,Proteins, Complement,Proteins, Complement System
D003176	Complement C3	A glycoprotein that is central in both the classical and the alternative pathway of COMPLEMENT ACTIVATION. C3 can be cleaved into COMPLEMENT C3A and COMPLEMENT C3B, spontaneously at low level or by C3 CONVERTASE at high level. The smaller fragment C3a is an ANAPHYLATOXIN and mediator of local inflammatory process. The larger fragment C3b binds with C3 convertase to form C5 convertase.	C3 Complement,C3 Precursor,Complement 3,Complement C3 Precursor,Complement Component 3,Precursor-Complement 3,Pro-C3,Pro-Complement 3,C3 Precursor, Complement,C3, Complement,Complement, C3,Component 3, Complement,Precursor Complement 3,Precursor, C3,Precursor, Complement C3,Pro C3,Pro Complement 3
D005921	Glomerulonephritis	Inflammation of the renal glomeruli (KIDNEY GLOMERULUS) that can be classified by the type of glomerular injuries including antibody deposition, complement activation, cellular proliferation, and glomerulosclerosis. These structural and functional abnormalities usually lead to HEMATURIA; PROTEINURIA; HYPERTENSION; and RENAL INSUFFICIENCY.	Bright Disease,Kidney Scarring,Glomerulonephritides,Scarring, Kidney
D013696	Temperature	The property of objects that determines the direction of heat flow when they are placed in direct thermal contact. The temperature is the energy of microscopic motions (vibrational and translational) of the particles of atoms.	Temperatures

Related Publications

F C Berthoux, and C B Carpenter, and J Traeger, and J P Merrill

Hypocomplementemic proliferative glomerulonephritis with C3 nephritic-factor-like activity in multiple myeloma.

January 1989, Nephron,

F C Berthoux, and C B Carpenter, and J Traeger, and J P Merrill

Significance of C3 nephritic factor (C3NeF) in non-hypocomplementaemic serum with membranoproliferative glomerulonephritis (MPGN).

September 1992, Clinical and experimental immunology,

F C Berthoux, and C B Carpenter, and J Traeger, and J P Merrill

Two types of C3 nephritic factor: properdin-dependent C3NeF and properdin-independent C3NeF.

August 1990, Clinical immunology and immunopathology,

F C Berthoux, and C B Carpenter, and J Traeger, and J P Merrill

Hypocomplementaemia of poststreptococcal acute glomerulonephritis is associated with C3 nephritic factor (C3NeF) IgG autoantibody activity.

January 1994, Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association,

F C Berthoux, and C B Carpenter, and J Traeger, and J P Merrill

[Chronic urticaria and acquired complement deficiency due to a nephritic factor (C3NeF)].

August 1990, Schweizerische medizinische Wochenschrift,

F C Berthoux, and C B Carpenter, and J Traeger, and J P Merrill

C3 nephritic factor and mesangiocapillary glomerulonephritis.

February 1997, Pediatric nephrology (Berlin, Germany),

F C Berthoux, and C B Carpenter, and J Traeger, and J P Merrill

Further evidence for the antibody nature of C3 nephritic factor (C3NeF).

August 1979, Journal of immunology (Baltimore, Md. : 1950),

F C Berthoux, and C B Carpenter, and J Traeger, and J P Merrill

Mesangiocapillary glomerulonephritis associated with meningococcal meningitis, C3 nephritic factor and persistently low complement C3 and C5.

May 1992, Pediatric nephrology (Berlin, Germany),