3'-L-Monoiodothyronine: development of a radioimmunoassay and demonstration of in vivo conversion from 3',5'-diiodothyronine.
1979
R C Smallridge, and
L Wartofsky, and
B J Green, and
F C Miller, and
K D Burman
UI
MeSH Term
Description
Entries
D011863
Radioimmunoassay
Classic quantitative assay for detection of antigen-antibody reactions using a radioactively labeled substance (radioligand) either directly or indirectly to measure the binding of the unlabeled substance to a specific antibody or other receptor system. Non-immunogenic substances (e.g., haptens) can be measured if coupled to larger carrier proteins (e.g., bovine gamma-globulin or human serum albumin) capable of inducing antibody formation.
Radioimmunoassays
D003429
Cross Reactions
Serological reactions in which an antiserum against one antigen reacts with a non-identical but closely related antigen.
Cross Reaction,Reaction, Cross,Reactions, Cross
D004104
Diiodothyronines
These metabolites of THYROXINE are formed by the deiodination of T3 or reverse T3.
D006801
Humans
Members of the species Homo sapiens.
Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D013961
Thyroid Gland
A highly vascularized endocrine gland consisting of two lobes joined by a thin band of tissue with one lobe on each side of the TRACHEA. It secretes THYROID HORMONES from the follicular cells and CALCITONIN from the parafollicular cells thereby regulating METABOLISM and CALCIUM level in blood, respectively.
A group of metabolites derived from THYROXINE and TRIIODOTHYRONINE via the peripheral enzymatic removal of iodines from the thyroxine nucleus. Thyronine is the thyroxine nucleus devoid of its four iodine atoms.
Thyronine
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R C Smallridge, and
L Wartofsky, and
B J Green, and
F C Miller, and
K D Burman