Biomaterial Database

[Change in the content and makeup of the phospholipids in the microsomal fraction of rat skeletal muscles under the influence of a flight on the Kosmos-690 biosatellite]. 1979

R A Belitskaia

The content and composition of phospholipids in the microsomes isolated from the back femoral muscles of rats flown for 20.5 days aboard the biosatellite Cosmos-690 were studied. Gamma-irradiation applied in the ground-based control experiments did not change the amount of total phospholipids in microsomes of skeletal muscles and altered insignificantly the content of their individual fractions. On the 2nd postflight day a substantial increase in the content of total and fractional phospholipids in microsomes was found. The decrease seems to be induced by weightlessness. On the 26th postflight day the content of total phospholipids returned to the normal whereas their fractional composition still remained changed.

UI	MeSH Term	Description	Entries
D008861	Microsomes	Artifactual vesicles formed from the endoplasmic reticulum when cells are disrupted. They are isolated by differential centrifugation and are composed of three structural features: rough vesicles, smooth vesicles, and ribosomes. Numerous enzyme activities are associated with the microsomal fraction. (Glick, Glossary of Biochemistry and Molecular Biology, 1990; from Rieger et al., Glossary of Genetics: Classical and Molecular, 5th ed)	Microsome
D009132	Muscles	Contractile tissue that produces movement in animals.	Muscle Tissue,Muscle,Muscle Tissues,Tissue, Muscle,Tissues, Muscle
D010743	Phospholipids	Lipids containing one or more phosphate groups, particularly those derived from either glycerol (phosphoglycerides see GLYCEROPHOSPHOLIPIDS) or sphingosine (SPHINGOLIPIDS). They are polar lipids that are of great importance for the structure and function of cell membranes and are the most abundant of membrane lipids, although not stored in large amounts in the system.	Phosphatides,Phospholipid
D000818	Animals	Unicellular or multicellular, heterotrophic organisms, that have sensation and the power of voluntary movement. Under the older five kingdom paradigm, Animalia was one of the kingdoms. Under the modern three domain model, Animalia represents one of the many groups in the domain EUKARYOTA.	Animal,Metazoa,Animalia
D013026	Space Flight	Travel beyond the earth's atmosphere.	Space Exploration,Space Travel,Spaceflight,Exploration, Space,Explorations, Space,Flight, Space,Flights, Space,Space Explorations,Space Flights,Space Travels,Spaceflights,Travel, Space,Travels, Space
D013997	Time Factors	Elements of limited time intervals, contributing to particular results or situations.	Time Series,Factor, Time,Time Factor
D014586	USSR	A country located from the Baltic and Black seas to the Pacific Ocean and, for a time including 15 Soviet Socialist Republics. The capital was Moscow.	Soviet Union,Union of Soviet Socialist Republics
D051381	Rats	The common name for the genus Rattus.	Rattus,Rats, Laboratory,Rats, Norway,Rattus norvegicus,Laboratory Rat,Laboratory Rats,Norway Rat,Norway Rats,Rat,Rat, Laboratory,Rat, Norway,norvegicus, Rattus