A product of the lysis of plasminogen (profibrinolysin) by PLASMINOGEN activators. It is composed of two polypeptide chains, light (B) and heavy (A), with a molecular weight of 75,000. It is the major proteolytic enzyme involved in blood clot retraction or the lysis of fibrin and quickly inactivated by antiplasmins.
The outer covering of the body that protects it from the environment. It is composed of the DERMIS and the EPIDERMIS.
D012871
Skin Diseases
Diseases involving the DERMIS or EPIDERMIS.
Dermatoses,Skin and Subcutaneous Tissue Disorders,Dermatosis,Skin Disease
D014652
Vascular Diseases
Pathological processes involving any of the BLOOD VESSELS in the cardiac or peripheral circulation. They include diseases of ARTERIES; VEINS; and rest of the vasculature system in the body.