BIOMAT Database Logo BIOMAT Database Logo

Studies on the relationship between 5-hydroxytryptamine turnover in brain and tolerance and physical dependence in mice. 1971

Y Maruyama, and G Hayashi, and S E Smits, and A E Takemori

UI MeSH Term Description Entries
D007981 Levorphanol A narcotic analgesic that may be habit-forming. It is nearly as effective orally as by injection. Levorphan,3-Hydroxy-N-methylmorphinan,L-Dromoran,Levo-Dromoran,Levodroman,Levorphanol Tartrate,3 Hydroxy N methylmorphinan,L Dromoran,Levo Dromoran,LevoDromoran,Tartrate, Levorphanol
D008297 Male Males
D008691 Methadone A synthetic opioid that is used as the hydrochloride. It is an opioid analgesic that is primarily a mu-opioid agonist. It has actions and uses similar to those of MORPHINE. (From Martindale, The Extra Pharmacopoeia, 30th ed, p1082-3) Amidone,Biodone,Dolophine,Metadol,Metasedin,Methaddict,Methadone Hydrochloride,Methadose,Methex,Phenadone,Phymet,Physeptone,Pinadone,Symoron,Hydrochloride, Methadone
D009019 Morphinans Compounds based on a partially saturated iminoethanophenanthrene, which can be described as ethylimino-bridged benzo-decahydronaphthalenes. They include some of the OPIOIDS found in PAPAVER that are used as ANALGESICS. Morphinan
D009020 Morphine The principal alkaloid in opium and the prototype opiate analgesic and narcotic. Morphine has widespread effects in the central nervous system and on smooth muscle. Morphine Sulfate,Duramorph,MS Contin,Morphia,Morphine Chloride,Morphine Sulfate (2:1), Anhydrous,Morphine Sulfate (2:1), Pentahydrate,Oramorph SR,SDZ 202-250,SDZ202-250,Chloride, Morphine,Contin, MS,SDZ 202 250,SDZ 202250,SDZ202 250,SDZ202250,Sulfate, Morphine
D009021 Morphine Dependence Strong dependence, both physiological and emotional, upon morphine. Morphine Abuse,Morphine Addiction,Abuse, Morphine,Addiction, Morphine,Dependence, Morphine
D009269 Nalorphine A narcotic antagonist with some agonist properties. It is an antagonist at mu opioid receptors and an agonist at kappa opioid receptors. Given alone it produces a broad spectrum of unpleasant effects and it is considered to be clinically obsolete. Allylnormorphine,Lethidrone,Nalorphine Hydrobromide,Nalorphine Hydrochloride,Nalorphine, (14 alpha)-Isomer,Nalorphine, L-tartrate (1:1),Hydrobromide, Nalorphine,Hydrochloride, Nalorphine
D010134 Fenclonine A selective and irreversible inhibitor of tryptophan hydroxylase, a rate-limiting enzyme in the biosynthesis of serotonin (5-HYDROXYTRYPTAMINE). Fenclonine acts pharmacologically to deplete endogenous levels of serotonin. p-Chlorophenylalanine,para-Chlorophenylalanine,CP-10,188,DL-3-(4-Chlorophenyl)alanine,Fenclonin,Fenclonine (L)-Isomer,Fenclonine Hydrobromide,Fenclonine Hydrochloride,Fenclonine, (D)-Isomer,Hydrobromide, Fenclonine,Hydrochloride, Fenclonine,para Chlorophenylalanine
D010293 Pargyline A monoamine oxidase inhibitor with antihypertensive properties. Pargyline Hydrochloride,Hydrochloride, Pargyline
D010423 Pentazocine The first mixed agonist-antagonist analgesic to be marketed. It is an agonist at the kappa and sigma opioid receptors and has a weak antagonist action at the mu receptor. (From AMA Drug Evaluations Annual, 1991, p97) Fortral,Lexir,Pentazocine Hydrochloride,Pentazocine Lactate,Talwin,Hydrochloride, Pentazocine,Lactate, Pentazocine

Related Publications

Y Maruyama, and G Hayashi, and S E Smits, and A E Takemori
Morphine tolerance, physical dependence, and synthesis of brain 5-hydroxytryptamine.
December 1968, Science (New York, N.Y.),
Y Maruyama, and G Hayashi, and S E Smits, and A E Takemori
Brain 5-hydroxytryptamine and cyclic AMP in morphine tolerance and dependence.
January 1974, Advances in biochemical psychopharmacology,
Y Maruyama, and G Hayashi, and S E Smits, and A E Takemori
Influence of p-chlorophenylalanine on morphine tolerance and physical dependence and regional brain serotonin turnover studies in morphine tolerant-dependent mice.
July 1972, The Journal of pharmacology and experimental therapeutics,
Y Maruyama, and G Hayashi, and S E Smits, and A E Takemori
Experimental observations on the relationship between ethanol tolerance and physical dependence.
December 1979, The British journal of addiction to alcohol and other drugs,
Y Maruyama, and G Hayashi, and S E Smits, and A E Takemori
Effects of social stress on the turnover of brain catecholamines and 5-hydroxytryptamine in mice.
February 1974, Acta pharmacologica et toxicologica,
Y Maruyama, and G Hayashi, and S E Smits, and A E Takemori
Isolation, aggressiveness and brain 5-hydroxytryptamine turnover.
May 1967, The Journal of pharmacy and pharmacology,
Y Maruyama, and G Hayashi, and S E Smits, and A E Takemori
Narcotic tolerance and dependence: lack of relationship with serotonin turnover in the brain.
March 1971, Science (New York, N.Y.),
Y Maruyama, and G Hayashi, and S E Smits, and A E Takemori
Evidence against a role of brain 5-hydroxytryptamine in the development of physical dependence upon morphine in mice.
December 1971, The Journal of pharmacology and experimental therapeutics,
Y Maruyama, and G Hayashi, and S E Smits, and A E Takemori
The effect of methysergide on 5-hydroxytryptamine turnover in whole brain.
May 1976, The Journal of pharmacy and pharmacology,
Y Maruyama, and G Hayashi, and S E Smits, and A E Takemori
Effect of ethanol on 5-hydroxytryptamine turnover in rat brain.
May 1970, Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.),
Copied contents to your clipboard!