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[Importance of chemico-biological interactions for the toxic and carcinogenic effects of aromatic amines. II. Distribution of radioactivity after administration of tritium labelled carcinogen trans-4-dimethylaminostilbene and the noncarcinogenic cis-4-dimethylaminostilbene and dimethyl aminobibenzyl in the rat]. 1971

H K Rjosk, and H G Neumann

UI MeSH Term Description Entries
D008657 Metabolic Clearance Rate Volume of biological fluid completely cleared of drug metabolites as measured in unit time. Elimination occurs as a result of metabolic processes in the kidney, liver, saliva, sweat, intestine, heart, brain, or other site. Total Body Clearance Rate,Clearance Rate, Metabolic,Clearance Rates, Metabolic,Metabolic Clearance Rates,Rate, Metabolic Clearance,Rates, Metabolic Clearance
D002273 Carcinogens Substances that increase the risk of NEOPLASMS in humans or animals. Both genotoxic chemicals, which affect DNA directly, and nongenotoxic chemicals, which induce neoplasms by other mechanism, are included. Carcinogen,Oncogen,Oncogens,Tumor Initiator,Tumor Initiators,Tumor Promoter,Tumor Promoters,Initiator, Tumor,Initiators, Tumor,Promoter, Tumor,Promoters, Tumor
D000818 Animals Unicellular or multicellular, heterotrophic organisms, that have sensation and the power of voluntary movement. Under the older five kingdom paradigm, Animalia was one of the kingdoms. Under the modern three domain model, Animalia represents one of the many groups in the domain EUKARYOTA. Animal,Metazoa,Animalia
D001593 Benzyl Compounds Benzene derivatives that contain a benzyl group with the general formula Phenyl-CH2-R. Compounds, Benzyl
D001632 Bibenzyls Compounds that include 1,2-diphenylethane in their structure. Bisbenzyls
D001692 Biological Transport The movement of materials (including biochemical substances and drugs) through a biological system at the cellular level. The transport can be across cell membranes and epithelial layers. It also can occur within intracellular compartments and extracellular compartments. Transport, Biological,Biologic Transport,Transport, Biologic
D001711 Biotransformation The chemical alteration of an exogenous substance by or in a biological system. The alteration may inactivate the compound or it may result in the production of an active metabolite of an inactive parent compound. The alterations may be divided into METABOLIC DETOXICATION, PHASE I and METABOLIC DETOXICATION, PHASE II.
D013267 Stilbenes Organic compounds that contain 1,2-diphenylethylene as a functional group. Stilbene,Stilbene Derivative,Stilbene Derivatives,Stilbenoid,Stilbenoids,Derivative, Stilbene,Derivatives, Stilbene
D014316 Tritium The radioactive isotope of hydrogen also known as hydrogen-3. It contains two NEUTRONS and one PROTON in its nucleus and decays to produce low energy BETA PARTICLES. Hydrogen-3,Hydrogen 3
D051381 Rats The common name for the genus Rattus. Rattus,Rats, Laboratory,Rats, Norway,Rattus norvegicus,Laboratory Rat,Laboratory Rats,Norway Rat,Norway Rats,Rat,Rat, Laboratory,Rat, Norway,norvegicus, Rattus

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H K Rjosk, and H G Neumann
[Importance of chemico-biological interactions for the toxic and carcinogenic effect of aromatic amines. IV. Metabolic patterns of trans-4-demethylaminostilbene, cis-4-dimethylaminostilbene and 4-dimethylaminobibenzyl in liver, kidney and excretion products of the rat].
January 1971, Zeitschrift fur Krebsforschung und klinische Onkologie. Cancer research and clinical oncology,
H K Rjosk, and H G Neumann
[The relevance of chemico-biological interactions for the toxic and carcinogenic effects of aromatic amines. I. Carcinogenic activity of some 4-aminostilbene and 4-aminobibenzyl-derivatives].
January 1970, Zeitschrift fur Krebsforschung,
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The relevance of chemico-biological interactions for the toxic and carcinogenic effects of aromatic amines. V. The pharmacokinetics of related aromatic amines in blood.
May 1972, Chemico-biological interactions,
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Tissue specific, acute toxic effects of the carcinogen trans-4-dimethylaminostilbene.
January 1985, Archives of toxicology,
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Distribution of radioactivity following oral administration of carcinogenic 14CH3-labelled nitrosocarbaryl in the rat.
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Autoradiographic study of the distribution of radioactivity in mice after oral administration of tritium-labelled orphenadrine hydrochloride.
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Distribution, excretion, and binding of radioactivity in the rat after intraperitoneal administration of the lung-toxic furan, [14C]4-Ipomeanol.
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[Distribution and metabolic rate of activity of tritium-labelled histidine in rat organs after oral administration].
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Distribution of tritium labelled delta 1-tetrahydrocannabinol in the rat brain following intraperitoneal administration.
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[Distribution of radioactivity in the organism and in exercretions of the rat after application of 14C-labelled 1-para-chlorophenyl-2,3-dimethyl-4--dimethylamino-butanol-2-HC1].
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