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Lymphoid cell lines. Established from peripheral blood of persons with Down's syndrome. 1973

L K Woods, and G E Moore, and C J Bainbridge, and C C Huang, and C Huzella, and L A Quinn

UI MeSH Term Description Entries
D007621 Karyotyping Mapping of the KARYOTYPE of a cell. Karyotype Analysis Methods,Analysis Method, Karyotype,Analysis Methods, Karyotype,Karyotype Analysis Method,Karyotypings,Method, Karyotype Analysis,Methods, Karyotype Analysis
D008214 Lymphocytes White blood cells formed in the body's lymphoid tissue. The nucleus is round or ovoid with coarse, irregularly clumped chromatin while the cytoplasm is typically pale blue with azurophilic (if any) granules. Most lymphocytes can be classified as either T or B (with subpopulations of each), or NATURAL KILLER CELLS. Lymphoid Cells,Cell, Lymphoid,Cells, Lymphoid,Lymphocyte,Lymphoid Cell
D008297 Male Males
D008875 Middle Aged An adult aged 45 - 64 years. Middle Age
D002460 Cell Line Established cell cultures that have the potential to propagate indefinitely. Cell Lines,Line, Cell,Lines, Cell
D002648 Child A person 6 to 12 years of age. An individual 2 to 5 years old is CHILD, PRESCHOOL. Children
D002675 Child, Preschool A child between the ages of 2 and 5. Children, Preschool,Preschool Child,Preschool Children
D004314 Down Syndrome A chromosome disorder associated either with an extra CHROMOSOME 21 or an effective TRISOMY for chromosome 21. Clinical manifestations include HYPOTONIA, short stature, BRACHYCEPHALY, upslanting palpebral fissures, epicanthus, Brushfield spots on the iris, protruding tongue, small ears, short, broad hands, fifth finger clinodactyly, single transverse palmar crease, and moderate to severe INTELLECTUAL DISABILITY. Cardiac and gastrointestinal malformations, a marked increase in the incidence of LEUKEMIA, and the early onset of ALZHEIMER DISEASE are also associated with this condition. Pathologic features include the development of NEUROFIBRILLARY TANGLES in neurons and the deposition of AMYLOID BETA-PROTEIN, similar to the pathology of ALZHEIMER DISEASE. (Menkes, Textbook of Child Neurology, 5th ed, p213) Mongolism,Trisomy 21,47,XX,+21,47,XY,+21,Down Syndrome, Partial Trisomy 21,Down's Syndrome,Partial Trisomy 21 Down Syndrome,Trisomy 21, Meiotic Nondisjunction,Trisomy 21, Mitotic Nondisjunction,Trisomy G,Downs Syndrome,Syndrome, Down,Syndrome, Down's
D005260 Female Females
D006801 Humans Members of the species Homo sapiens. Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man

Related Publications

L K Woods, and G E Moore, and C J Bainbridge, and C C Huang, and C Huzella, and L A Quinn
[Characterization of B cell lines spontaneously established from the peripheral blood of Sjögren's syndrome].
July 1986, Arerugi = [Allergy],
L K Woods, and G E Moore, and C J Bainbridge, and C C Huang, and C Huzella, and L A Quinn
Peripheral blood cell counts in infants with Down's syndrome.
January 1996, Clinical genetics,
L K Woods, and G E Moore, and C J Bainbridge, and C C Huang, and C Huzella, and L A Quinn
Initiation and establishment of lymphoid cell lines from the blood of healthy persons.
August 1971, Journal of the National Cancer Institute,
L K Woods, and G E Moore, and C J Bainbridge, and C C Huang, and C Huzella, and L A Quinn
Comparison of radiosensitivity between human hematopoietic cell lines derived from patients with Down's syndrome and from normal persons.
July 1977, Journal of the National Cancer Institute,
L K Woods, and G E Moore, and C J Bainbridge, and C C Huang, and C Huzella, and L A Quinn
Lysosomal hydrolases in established lymphoid cell lines.
May 1980, Biomedicine / [publiee pour l'A.A.I.C.I.G.],
L K Woods, and G E Moore, and C J Bainbridge, and C C Huang, and C Huzella, and L A Quinn
Interaction between peripheral blood leucocytes and x-irradiated cells from lymphoid cell lines.
April 1969, Experientia,
L K Woods, and G E Moore, and C J Bainbridge, and C C Huang, and C Huzella, and L A Quinn
Graft-versus-host reactivity of human lymphoid cells from established cell lines.
October 1971, Cellular immunology,
L K Woods, and G E Moore, and C J Bainbridge, and C C Huang, and C Huzella, and L A Quinn
An analysis of polyclonal B cell activation in Sjögren's syndrome. Characterization of B cell lines spontaneously established from the peripheral blood.
January 1986, Scandinavian journal of rheumatology. Supplement,
L K Woods, and G E Moore, and C J Bainbridge, and C C Huang, and C Huzella, and L A Quinn
Enhanced destruction of lymphoid cell lines by peripheral blood leukocytes taken from patients with acute infectious mononucleosis.
July 1975, Journal of immunology (Baltimore, Md. : 1950),
L K Woods, and G E Moore, and C J Bainbridge, and C C Huang, and C Huzella, and L A Quinn
Chromosomes of 14 hematopoietic cell lines derived from peripheral blood of persons with and without chromosome anomalies.
November 1969, Journal of the National Cancer Institute,
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