Mediastinal lymph node biopsy in sarcoidosis. 1979

J R Mikhail, and M Shepherd, and D N Mitchell

Mediastinoscopy, in the skilled hands of a thoracic surgeon has proved to be a safe, cosmetically accepted procedure with negligible complications. It has yielded a high rate of diagnostic lymph node tissue; overall greater than 82% among patients with sarcoidosis, including patients presenting with pulmonary mottling only or with a normal chest radiograph. Among patients with lymphatic tuberculosis it enabled the isolation of human M. tuberculosis following culture of the lymph node removed on Löwenstein-Jensen medium in greater than 79% of cases. A precise histological diagnosis was obtained in all 14 patients presenting with hilar and/or paratracheal lymphadenopathy attributable to malignant disease.

UI MeSH Term Description Entries
D007731 Kveim Test Intradermal injection of a heated (pasteurized) saline suspension of sarcoid tissue obtained from a sarcoid spleen or lymph node. In patients with active sarcoidosis a dusky red nodule develops slowly over the next few weeks at the injection site. Histologic examination, an essential part of the complete test, reveals sarcoid tissue. Test, Kveim
D008198 Lymph Nodes They are oval or bean shaped bodies (1 - 30 mm in diameter) located along the lymphatic system. Lymph Node,Node, Lymph,Nodes, Lymph
D008481 Mediastinoscopy Endoscopic examination, therapy or surgery of the anterior superior mediastinum of the thorax. Mediastinoscopic Surgical Procedures,Surgical Procedures, Mediastinoscopic,Mediastinoscopic Surgery,Surgery, Mediastinoscopic,Mediastinoscopic Surgeries,Mediastinoscopic Surgical Procedure,Mediastinoscopies,Procedure, Mediastinoscopic Surgical,Procedures, Mediastinoscopic Surgical,Surgeries, Mediastinoscopic,Surgical Procedure, Mediastinoscopic
D011859 Radiography Examination of any part of the body for diagnostic purposes by means of X-RAYS or GAMMA RAYS, recording the image on a sensitized surface (such as photographic film). Radiology, Diagnostic X-Ray,Roentgenography,X-Ray, Diagnostic,Diagnostic X-Ray,Diagnostic X-Ray Radiology,X-Ray Radiology, Diagnostic,Diagnostic X Ray,Diagnostic X Ray Radiology,Diagnostic X-Rays,Radiology, Diagnostic X Ray,X Ray Radiology, Diagnostic,X Ray, Diagnostic,X-Rays, Diagnostic
D005260 Female Females
D006801 Humans Members of the species Homo sapiens. Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D000328 Adult A person having attained full growth or maturity. Adults are of 19 through 44 years of age. For a person between 19 and 24 years of age, YOUNG ADULT is available. Adults
D001706 Biopsy Removal and pathologic examination of specimens from the living body. Biopsies
D012507 Sarcoidosis An idiopathic systemic inflammatory granulomatous disorder comprised of epithelioid and multinucleated giant cells with little necrosis. It usually invades the lungs with fibrosis and may also involve lymph nodes, skin, liver, spleen, eyes, phalangeal bones, and parotid glands. Besnier-Boeck Disease,Boeck's Sarcoid,Besnier-Boeck-Schaumann Syndrome,Boeck Disease,Boeck's Disease,Schaumann Disease,Schaumann Syndrome,Schaumann's Syndrome,Besnier Boeck Disease,Besnier Boeck Schaumann Syndrome,Boeck Sarcoid,Boecks Disease,Boecks Sarcoid,Disease, Schaumann,Sarcoid, Boeck's,Sarcoidoses,Schaumann's Syndromes,Syndrome, Besnier-Boeck-Schaumann,Syndrome, Schaumann,Syndrome, Schaumann's
D014388 Tuberculosis, Lymph Node Infection of the lymph nodes by tuberculosis. Tuberculous infection of the cervical lymph nodes is scrofula. Cervical Tuberculous Lymphadenitis,Lymphadenitis, Tuberculous,Mycobacterial Cervical Lymphadenitis,Scrofula,Cervical Lymphadenitis, Mycobacterial,Lymph Node Tuberculoses,Lymph Node Tuberculosis,Lymphadenitis, Cervical Tuberculous,Lymphadenitis, Mycobacterial Cervical,Scrofulas,Tuberculoses, Lymph Node,Tuberculous Lymphadenitis,Tuberculous Lymphadenitis, Cervical

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