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Studies on the mechanism of squalene biosynthesis. Presqualene pyrophosphate, stereochemistry and a mechanism for its conversion to squalene.
1971
H C Rilling, and C D Poulter, and W W Epstein, and B Larsen
Associated MeSH Terms
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MeSH Term
Description
Entries
D011756
Diphosphates
Inorganic salts of phosphoric acid that contain two phosphate groups.
Diphosphate,Pyrophosphate Analog,Pyrophosphates,Pyrophosphate Analogs,Analog, Pyrophosphate
D013185
Squalene
A natural 30-carbon triterpene.
D013237
Stereoisomerism
The phenomenon whereby compounds whose molecules have the same number and kind of atoms and the same atomic arrangement, but differ in their spatial relationships. (From McGraw-Hill Dictionary of Scientific and Technical Terms, 5th ed)
Molecular Stereochemistry,Stereoisomers,Stereochemistry, Molecular,Stereoisomer
Related Publications
H C Rilling, and C D Poulter, and W W Epstein, and B Larsen
Mechanism of presqualene pyrophosphate-squalene biosynthesis.
April 1971, Journal of the American Chemical Society,
H C Rilling, and C D Poulter, and W W Epstein, and B Larsen
Studies on the mechanism of squalene biosynthesis. The structure of presqualene pyrophosphate.
September 1970, The Journal of biological chemistry,
H C Rilling, and C D Poulter, and W W Epstein, and B Larsen
STEREOCHEMISTRY AT THE CENTER OF SQUALENE DURING ITS BIOSYNTHESIS FROM FARNESYL PYROPHOSPHATE AND SUBSEQUENT CONVERSION TO CHOLESTEROL.
January 1964, The Journal of biological chemistry,
H C Rilling, and C D Poulter, and W W Epstein, and B Larsen
Stereochemistry of the hydrogen transfer to squalene during its biosynthesis from farnesyl pyrophosphate.
April 1963, Biochemical and biophysical research communications,
H C Rilling, and C D Poulter, and W W Epstein, and B Larsen
Synthesis and conversion of presqualene alcohol to squalene.
April 1971, Journal of the American Chemical Society,
H C Rilling, and C D Poulter, and W W Epstein, and B Larsen
The conversion of presqualene pyrophosphate into squalene by a cell-free preparation of Pisum sativum.
December 1972, FEBS letters,
H C Rilling, and C D Poulter, and W W Epstein, and B Larsen
Recombinant squalene synthase. A mechanism for the rearrangement of presqualene diphosphate to squalene.
July 2002, Journal of the American Chemical Society,
H C Rilling, and C D Poulter, and W W Epstein, and B Larsen
Squalene synthetase. Stoichiometry and kinetics of presqualene pyrophosphate and squalene synthesis by yeast microsomes.
July 1978, The Journal of biological chemistry,
H C Rilling, and C D Poulter, and W W Epstein, and B Larsen
Studies on the biosynthesis of cholesterol. XV. Mechanism of squalene biosynthesis from farnesyl pyrophosphate and from mevalonate.
July 1961, The Journal of biological chemistry,
H C Rilling, and C D Poulter, and W W Epstein, and B Larsen
Biosynthesis of presqualene pyrophosphate by liver microsomes.
September 1970, Journal of lipid research,
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