Biomaterial Database

[Sclerosing lipogranuloma of male genitalia (author's transl)]. 1979

A H Hölscher, and G Rahlf, and A Zimmermann

The term "sclerosing lipogranuloma" was coined in 1950 to name a peculiar granulomatous fatty tissue reaction that according to Smetana and Bernhard represents a "local reactive process which sometimes follows injury to subcutaneous fat tissue". Later other investigators have pointed out that injections of exogenous lipids probably cause this lesion. A case of sclerosing lipogranuloma in the scrotum is presented, in which paraffin hydrocarbon could be identified. As prior to the appearance of the lipogranuloma a paraffin containing ointment had been applied locally for three weeks a percutaneous resorption of paraffin as a possible etiology is discussed together with a review of the literature.

UI	MeSH Term	Description	Entries
D008297	Male		Males
D008875	Middle Aged	An adult aged 45 - 64 years.	Middle Age
D009824	Ointments	Semisolid preparations used topically for protective emollient effects or as a vehicle for local administration of medications. Ointment bases are various mixtures of fats, waxes, animal and plant oils and solid and liquid hydrocarbons.	Ointment,Paste,Pastes,Salve,Unguent,Salves,Skin Ointment,Unguents,Ointment, Skin
D010232	Paraffin	A mixture of solid hydrocarbons obtained from petroleum. It has a wide range of uses including as a stiffening agent in ointments, as a lubricant, and as a topical anti-inflammatory. It is also commonly used as an embedding material in histology.	Parafilm
D006099	Granuloma	A relatively small nodular inflammatory lesion containing grouped mononuclear phagocytes, caused by infectious and noninfectious agents.	Granulomas
D006801	Humans	Members of the species Homo sapiens.	Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D000287	Administration, Topical	The application of drug preparations to the surfaces of the body, especially the skin (ADMINISTRATION, CUTANEOUS) or mucous membranes. This method of treatment is used to avoid systemic side effects when high doses are required at a localized area or as an alternative systemic administration route, to avoid hepatic processing for example.	Drug Administration, Topical,Administration, Topical Drug,Topical Administration,Topical Drug Administration,Administrations, Topical,Administrations, Topical Drug,Drug Administrations, Topical,Topical Administrations,Topical Drug Administrations
D012611	Scrotum	A cutaneous pouch of skin containing the testicles and spermatic cords.	Scrotums