-transparent.png){kind=logo}
Infection of mouse embryo cells with two strains of murine sarcoma virus and one strain of murine leukemia virus was followed rapidly by synthesis of DNA in the cytoplasm. Persistently infected cells have not shown such synthesis, and ultraviolet-irradiated virus did not induce DNA synthesis. This new DNA presumably represents an intermediate in the virus replication cycle specified by the virion DNA polymerase(s). Failure to observe cytoplasmic DNA synthesis in persistently infected cells suggests, in keeping with the results of inhibitor experiments, that the new "viral" DNA becomes associated with cellular DNA in some form of stable interaction.
Related Publications
M Hatanaka, and
T Kakefuda, and
R V Gilden, and
E A Callan
October 1970,
Proceedings of the National Academy of Sciences of the United States of America,
M Hatanaka, and
T Kakefuda, and
R V Gilden, and
E A Callan
January 1972,
Advances in virus research,
M Hatanaka, and
T Kakefuda, and
R V Gilden, and
E A Callan
July 1970,
Deutsche medizinische Wochenschrift (1946),
M Hatanaka, and
T Kakefuda, and
R V Gilden, and
E A Callan
May 1972,
Hoppe-Seyler's Zeitschrift fur physiologische Chemie,
M Hatanaka, and
T Kakefuda, and
R V Gilden, and
E A Callan
October 1977,
Biochimica et biophysica acta,
M Hatanaka, and
T Kakefuda, and
R V Gilden, and
E A Callan
January 1979,
Cold Spring Harbor symposia on quantitative biology,
M Hatanaka, and
T Kakefuda, and
R V Gilden, and
E A Callan
November 1974,
Biochemical and biophysical research communications,
M Hatanaka, and
T Kakefuda, and
R V Gilden, and
E A Callan
July 1977,
Proceedings of the National Academy of Sciences of the United States of America,
M Hatanaka, and
T Kakefuda, and
R V Gilden, and
E A Callan
January 1979,
Current topics in microbiology and immunology,
M Hatanaka, and
T Kakefuda, and
R V Gilden, and
E A Callan
May 1984,
Medical hypotheses,
