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Antiserum to partially purified reverse transcriptase from the Schmidt-Ruppin strain of Rous sarcoma virus has been prepared and characterized. Antibody to the avian polymerase inhibited the reverse transcriptase activity of avian C-type viruses but had no effect on the polymerase activity from C-type viruses of other classes. The known mammalian C-type viral polymerases were significantly inhibited only by the antiserum to murine C-type viral polymerases; reverse transcriptases from four other mammalian viruses were immunologically distinct from both avian and mammalian C-type viral polymerases. Partially purified murine leukemia viral DNA polymerase activity was comparably reduced by specific antibody regardless of the template used for enzyme detection.
W P Parks, and
E M Scolnick, and
J Ross, and
G J Todaro, and
S A Aaronson
January 1975,
Biochemical and biophysical research communications,
W P Parks, and
E M Scolnick, and
J Ross, and
G J Todaro, and
S A Aaronson
July 1974,
Applied microbiology,
W P Parks, and
E M Scolnick, and
J Ross, and
G J Todaro, and
S A Aaronson
November 1966,
Virology,
W P Parks, and
E M Scolnick, and
J Ross, and
G J Todaro, and
S A Aaronson
August 1990,
Antimicrobial agents and chemotherapy,
W P Parks, and
E M Scolnick, and
J Ross, and
G J Todaro, and
S A Aaronson
August 1971,
Journal of virology,
W P Parks, and
E M Scolnick, and
J Ross, and
G J Todaro, and
S A Aaronson
October 1995,
The Journal of biological chemistry,
W P Parks, and
E M Scolnick, and
J Ross, and
G J Todaro, and
S A Aaronson
April 2017,
Virus research,
W P Parks, and
E M Scolnick, and
J Ross, and
G J Todaro, and
S A Aaronson
August 2010,
Cellular and molecular life sciences : CMLS,
W P Parks, and
E M Scolnick, and
J Ross, and
G J Todaro, and
S A Aaronson
January 1963,
Journal of molecular biology,
W P Parks, and
E M Scolnick, and
J Ross, and
G J Todaro, and
S A Aaronson
March 1974,
Biochemistry,
